Terminology Service < Semantic Lookup Platform

All terms in BAO

Label	Id	Description
gene overexpression by transient transfection	BAO_0002444
HL-60 cell	CLO_0003775
neonatal thyrotoxicosis	DOID_12573
thyrotoxicosis	DOID_7997	[A thyroid gland disease that is characterized by excess thyroid hormone.]
appendiceal neoplasm	DOID_11240
FDA-approved compound library	BAO_0700004	[Any compound library consisting solely of small molecules that have been approved by the FDA. Often used for 'drug re-purposing' assays. The specific compounds included in any given FDA-approved compound library may differ based on availability or timing.]
vitamin K deficiency hemorrhagic disease	DOID_11249
bivalent small molecule-peptide	BAO_0700003	[A synthetic ligand consisting of a small molecule tethered (covalently or non-covalently) to a peptide.]
disseminated intravascular coagulation	DOID_11247
urethral obstruction	DOID_12577
MTT reduction assay	BAO_0002457	[The MTT assay is a colorimetric assay that relies on the enzymatic reduction of a yellow tetrazolium salt, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT), which forms a purple formazan crystal in metabolically active cells. The formazan can then be solubilized producing a concentration dependent colorimetric signal at 570 nm proportional to the cell number and activity.]
XTT reduction assay	BAO_0002458	[The XTT Cell Proliferation Assay is a colorimetric assay system which measures the reduction of a tetrazolium component (XTT) into soluble formazan product by the mitochondria of viable cells. The samples are read using an ELISA plate reader at a wavelength of 450nm. The amount of color produced is directly proportional to the number of viable cells.]
resazurin reduction assay	BAO_0002459	[For spectrophotometric measurement of metabolic activity of living cells. Absorbance of converted dye is measured at a wavelength of 600 nm. Bioreduction of the dye reduces the amount of its oxidized form (blue) and concomitantly increases the fluorescent intermediate (red).]
beta-adrenergic receptor activity	GO_0004939	[Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.]
functionality	PATO_0001509	[A quality of a single physical entity that arises by virtue of whether the bearer exhibits the ability to perform a regular function(s).]
ER-associated misfolded protein catabolic process	GO_0071712	[The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation.]
nucleic acid amplification method	BAO_0002450	[A method that uses purified enzymes to isolate and then replicate specific nucleic acids to levels where they can be detected. Examples are PCR, TMA, NASBA, etc.]
progesterone receptor agonist	CHEBI_70709
chromosome mapping	BAO_0002451	[Mapping is the construction of a series of chromosome descriptions that depict the position and spacing of unique, identifiable biochemical landmarks, including some genes, that occur on the DNA of chromosomes.]
volumetric titration	BAO_0002454	[Method in which the amount of a substance is determined by measuring the volume of a second substance that combines or reacts with the first in known proportions.]