Terminology Service < Semantic Lookup Platform

All terms in BAO

Label	Id	Description
cytotoxicity	BAO_0000090	[It is the toxic or cell-death inducing property of a perturbagen. Known cytotoxic agents mediate cell death commonly by necrosis, apoptosis, or autophagy. Cytotoxicity can be detected by measuring various aspects of the death process: e.g. membrane permeability, ATP concentration, DNA fragmentation, etc.]
phenotypic mode of action	BAO_0080004
hemiplegia	DOID_10969
central nervous system disease	DOID_331	[A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system.]
wild type	BAO_0000089	[The phenotype of an organism that is most common in nature and was unmodified.]
methylated	BAO_0000088	[A quality of a DNA or RNA residue that has a methyl group attached to it.]
posttranscriptionally modified	BAO_0002158	[A quality of a DNA or RNA residue that has a group (e.g., methyl) attached to it after transcription.]
spastic hemiplegia	DOID_10967	[A spastic cerebral palsy that affects one side of the body resulting in stiff arm, hand and leg. On the affected side,the arm and leg may not develop normally.]
spastic cerebral palsy	DOID_0050669	[A cerebral palsy that is caused by damage in the outer layer of the brain, the cerebral cortex, which results in increased tone, or tension, in a muscle causing abnormal movements.]
activation	BAO_0000087	[Increase of a predefined stimulus. Unit of Measure is always % when normalized to the dynamic range of the assay.]
reversible binding	BAO_0000086	[In this assay, the interaction of the ligand with a receptor can be dissociated by changing the binding conditions, e.g. buffer, salt concentration, etc.]
ligand binding mode of action	BAO_0000476	[Concepts describing the type of perturbagen interaction with the receptor.]
spastic diplegia	DOID_10965	[A spastic cerebral palsy that affects lower extremities resulting in tight leg and hip muscles. The legs cross at the knees, making it difficult to walk.]
irreversible binding	BAO_0000085	[In this assay, the binding of the ligand to a receptor is permanent and cannot be dissociated by changing the binding conditions such as buffer, salt concentration, etc.]
mode of action	BAO_0000074	[This refers to the effect of the perturbagen on the target of an assay, whether it brings about inhibition, activation, cytotoxicity, etc. ]
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor	CHEBI_50423
EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor	CHEBI_76867
platelet aggregation inhibitor	CHEBI_50427
hematologic agent	CHEBI_50248
oophoritis	DOID_10974