Terminology Service for NFDI4Health
All terms in BAO
| Label | Id | Description |
|---|---|---|
| phosphoprotein-specific antibody-coated bead based method | BAO_0003025 | |
| binding type | BAO_0000041 | [Binding assays are performed to understand the interaction between two molecules, e.g. perturbagen-protein, protein-protein, protein-DNA, etc.] |
| conformation determination method | BAO_0000048 | [This technology relates to measurement of protein and nucleic acid conformational properties. Proteins undergo changes to their tertiary structure upon heating, binding to perturbagens, other proteins and substrates. Nucleic acids have characteristic secondary structures, which include the B-family of structures, A-form, Z-form, guanine quadruplexes, cytosine quadruplexes, triplexes, etc. Information about conformational properties of protein and nucleic acids can be obtained by circular dichroism spectroscopy, thermal shift, fluorescence resonance energy transfer (FRET), nuclear magnetic resonance (NMR), X-ray crystallography, etc.] |
| gibberellin biosynthesis inhibitor | CHEBI_73193 | |
| EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor | CHEBI_73192 | |
| EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor | CHEBI_76860 | |
| abscisic acid receptor agonist | CHEBI_73191 | |
| antimutagen | CHEBI_73190 | |
| impedance | BAO_0000061 | [Impedance biosensors measure the electrical opposition of an interface in AC steady state with constant DC bias conditions. This is accomplished by imposing a small sinusoidal voltage at a particular frequency and measuring the resulting current; the process can be repeated at different frequencies. The current-voltage ratio gives the impedance.] |
| current clamp | BAO_0000060 | [The current clamp technique is used to measure biological voltages such as the action potential of an excitable cell with a microelectrode while keeping electrical current through the recording electrode constant. It can be used for both extracellular and intracellular recordings.] |
| EC 4.4.1.11 (methionine gamma-lyase) inhibitor | CHEBI_73196 | |
| EC 4.4.1.* (C-S lyase) inhibitor | CHEBI_76831 | |
| thermal shift | BAO_0000058 | [Upon heating, a protein unfolds and loses the native conformation. Binding of a small molecule can often stabilize the protein conformation, resulting in a higher unfolding temperature. The temperature shift in unfolding can be detected using a fluorescent dye, which is sensitive to the protein environment.] |
| protein kinase B signaling | GO_0043491 | [A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.] |
| provitamin A | CHEBI_67200 | |
| provitamin | CHEBI_50188 | |
| mass spectrometry | BAO_0000055 | [This method is used to detect compounds that are bound to the protein targets. The unbound compounds are separated by affinity based, size exclusion, or ultrafiltration methods. The bound compounds are eluted from the protein and detected by mass spectrometry. Based on the separation method, the throughput varies: between 200-2700 compounds can be loaded in each run for separation. Mass spectrometry is used to determine the chemical structure of molecules. The samples are vaporized, followed by ionization and then the mass to charge ratio of the particles is analyzed.] |
| Velos-MS | BAO_0150092 | |
| epigenetic profile | BAO_0080032 | |
| protein level | BAO_0080027 |