Terminology Service < Semantic Lookup Platform

All terms in BAO

Label	Id	Description
EC 3.4.24.24 (gelatinase A) inhibitor	CHEBI_84036
cell membrane format	BAO_0000249	[The thin outer covering of a cell consisting of lipid-bilayer embedded with proteins. It is semi-permeable and is also called "plasma membrane"]
transient transfection	BAO_0000247	[It is the temporary introduction of a gene or siRNA encoding DNA of interest into a cell using various plasmids. Usually, the transiently transfected DNA remains in the cell for 2-3 days and is functional: expresses the gene of interest. There are numerous transient transfection reagents and protocols available that have been optimized for various cell lines.]
stable transfection	BAO_0000246	[In this method, the introduced plasmid construct is stably integrated in the cellular genome, and is hence a permanent modification of the cells. This is achieved by selecting for cells which express a plasmid-encoded selectable marker, which is commonly an antibiotic resistance protein.]
rabbit reticulocyte lysate format	BAO_0000255	[The lysate contains the cellular components necessary for in vitro protein synthesis (tRNA, ribosomes, amino acids, initiation, elongation and termination factors). It is prepared from rabbit reticulocytes by lysis, followed by treatment with micrococcal nuclease to destroy endogenous mRNA for background reduction.]
whole cell lysate format	BAO_0000254	[A cell whose membrane has been ruptured, either mechanically or by freeze-thawing. The entire cell lysate is used in the assay without extensive purification (or separation).]
nuclear extract format	BAO_0000253	[It is a soluble extract prepared from the cellular nuclei, which are obtained by differential centrifugation of the cell lysate.]
mitochondrion format	BAO_0000252	[An organelle found in the cytoplasm of eukaryotic cells that metabolizes glucose and other sugars to produce usable energy in the form of ATP. It contains its own genome which encodes proteins, tRNA and rRNA.]
microsome format	BAO_0000251	[Microsomes are vesicle-like structures formed as an artifact from the endoplasmic reticulum after the cell has been ruptured by homogenization.]
apoptotic	PATO_0000638	[A structural quality inhering in a bearer by virtue of the bearer's consisting of blebbing of the nucleus and DNA fragmentation due to the cell undergoing a specific form of programmed cell death termed apoptosis.]
cytosol format	BAO_0000250	[The fluid component of cytoplasm, without the organelles and the insoluble cytoplasmic components.]
schistosomicide drug	CHEBI_38941
antiplatyhelmintic drug	CHEBI_35684
propionic acidemia	DOID_14701	[An organic acidemia that involes a nonfunctional propionyl CoA carboxylase affecting conversion of aminio acids and fats into sugar for energy.]
branchiootorenal syndrome	DOID_14702
ECMax_fold increase	BAO_0002886	[The compound concentration whereupon perceived activity (fold increase) reaches the maximum value observed (with a positive control).]
ECMax	BAO_0002883	[The compound concentration whereupon perceived activity reaches the maximum value observed (with a positive control).]
protein complex format	BAO_0000223	[Two or more proteins interact to form a stable complex. Each of the members of this complex has a distinct role in mediating the overall function of the complex, which can be as a chaperone (DnaK, DnaJ and grpE), an enzyme (mitochondrial respiratory complexes), a signaling complex (G-proteins), etc. It can be viewed as a quaternary structure of the proteins.]
generic hydrolase	BAO_0000222	[Includes all hydrolases except phosphatases and proteases.]
hydrolase	BAO_0000287	[Formation of two products from a substrate by hydrolysis.]