Terminology Service < Semantic Lookup Platform

All terms in CL

Label	Id	Description
T2 B cell	CL_0000959	[A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive.]
T1 B cell	CL_0000958	[A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative.]
pre-B-I cell	CL_0000956	[A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.]
Bm2 B cell	CL_0000962	[A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.]
Bm1 B cell	CL_0000961	[A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.]
Fraction F mature B cell	CL_0002056	[A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative.]
negative regulation of intracellular protein transport	GO_0090317	[Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.]
T3 B cell	CL_0000960	[A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM).]
positive regulation of intracellular protein transport	GO_0090316	[Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.]
future pituitary gland	UBERON_0034875
Bm4 B cell	CL_0000966	[A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor.]
Bm3-delta B cell	CL_0000963	[A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive.]
Bm3 B cell	CL_0000965	[A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type.]
Bm2' B cell	CL_0000964	[A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative.]
regulatory B cell	CL_0000969	[A mature B cell that has the phenotype CD1d-positive and expresses interleukin-10. This cell type has been associated with suppression of chronic inflammatory responses and T cell responses.]
Bm5 B cell	CL_0000967	[A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes.]
white matter of medulla oblongata	UBERON_0014649	[A white matter that is part of a medulla oblongata.]
white matter of myelencephalon	UBERON_0019262	[A white matter that is part of the myelencephalon.]
tyrosine-protein phosphatase non-receptor type substrate 1 (rat)	PR_P97710	[A tyrosine-protein phosphatase non-receptor type substrate 1 that is encoded in the genome of rat.]
Sirpa (rat)	main.html	[A protein coding gene Sirpa in rat.]