Terminology Service for NFDI4Health
All terms in EFO
| Label | Id | Description |
|---|---|---|
| MM.1S | EFO_0005724 | [MM.1S is a B lymphoblast cell line derived in 1986. The parent cell line, MM.1, was established from peripheral blood of a multiple myeloma patient who had become resistant to steroid-based therapy. provide critical information about disease progression and the development of drug resistance. This cell line represents a valuable tool for elucidating the mechanisms of action of glucocorticoids and the development of new therapeutics. [PMID: 2926241]] |
| phospholipase A2 inhibitor | CHEBI_50469 | |
| BE(2)-C | EFO_0005725 | [BE(2)-C is a clone of the SK-N-BE(2) neuroblastoma cell line (ATCC CRL-2271) that was established in November of 1972 from a bone marrow biopsy taken from child with disseminated neuroblastoma after repeated courses of chemotherapy and radiotherapy. The cells grow as clusters of flattened neuroblastic cells with occasional fine cell processes (neurites). Unlike the parent line, they generally do not detach and float.] |
| HTR8/SVneo | EFO_0005709 | [First trimester human trophoblast cells established by immortalizing a physiologic extravillous trophoblast cell via transfection with a plasmid containing the simian virus 40 large T antigen (SV40) (see Graham et al., 1993). Cells are a thin layer of ectoderm that forms the wall of many mammalian blastulas and functions in the nutrition and implantation of the embryo.] |
| Mel-2183 | EFO_0005706 | [ in the Surgery Branch of the NCI.">This cell line was from a melanoma metastasis tumor taken from the subcutaneous shoulder of an individual. Cell line was derived by Dr. Yardena Samuels (samuelsy[at]mail.nih.gov)] |
| response to ximelagatran | GO_0036288 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to ximelagatran stimulus. Ximelagatran is a direct thrombin inhibitor and anticoagulant drug.] |
| 786-0 | EFO_0005707 | [This line was derived from a primary clear cell adenocarcinoma. The karyotype is hypertriploid; Y was present in 60% the cells examined. The cells display both microvilli and desmosomes, and can be grown in soft agar. The cells produce a PTH like peptides that is identical to peptides produced by breast and lung tumors.] |
| response to iloperidone | GO_0036287 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to iloperidone, an atypical antipsychotic used in the treatment of schizophrenia.] |
| osteosclerosis | MONDO_0002933 | [Abnormally high bone density.] |
| HPDE6-E6E7 | EFO_0005711 | [Normal benign adult human pancreatic duct cells immortalized with E6E7 gene of HPV-16. HPDE6-E6E7 cells demonstrated a near normal genotype and phenotype of pancreatic duct epithelial cells. [PMC1861644]] |
| CLN13 disease | Orphanet_352709 | |
| RPMI-7951 | EFO_0005712 | [Human skin malignant melanoma cells that can be ordered from ATCC. This is a hyperdiploid human cell line with the modal chromosome number of 49, occurring in 24% of cells. Polyploid cells occurred at 22%, which is high. Cells are adherent, and were first harvested in 1971 from a metastatic site in a lymph node.] |
| HFF-Myc | EFO_0005710 | [This is an adherent cell line. HFF-Myc are human foreskin fibroblasts containing a virally integrated vector expressing the canine cMyc gene. Cells were received from Dr. Beverly Torok-Storb, Fred Hutchison Cancer Research Center, Seattle, WA.] |
| WERI-Rb-1 | EFO_0005715 | [The WERI-Rb-1 line is one of two human retinoblastoma cell lines established in 1974 by R.M. McFall and T.W. Sery. This is a near diploid line. The modal chromosome number is 47 occurring at 38%, and the rate of polyploidy is 9%. Cells are grape-like clusters of round cells in suspension.] |
| 8988T | EFO_0005713 | [Human pancreas adenocarcinoma (PA-TU-8988T), "established in 1985 from the liver metastasis of a primary pancreatic adenocarcinoma from a 64-year-old woman; sister cell line of PA-TU-8988S" - DSMZ.] |
| LHCN-M2 | EFO_0005714 | [Skeletal myoblasts derived from satellite cells from the pectoralis major muscle of a 41 year old caucasian heart transplant donor, immortalized with lox-hygro-hTERT (LH), and Cdk4-neo (CN), Zhu et al. (2007) in Aging Cell, vol. 6, pp 515-523. M2 is an extremely well-differentiating subclone of LHCN (thus "LHCN-M2").] |
| Facial dysmorphism - immunodeficiency - livedo - short stature | Orphanet_352712 | |
| obsolete_induced pluripotent stem cell | EFO_0005739 | [Induced pluripotent stem cells (iPSCs) are adult cells that have been genetically reprogrammed to an embryonic stem cell–like state by being forced to express genes and factors important for maintaining the defining properties of embryonic stem cells. ] |
| sodium valproate | CHEBI_9925 | [The sodium salt of valproic acid., Encoded by HOXC6 Gene (ANTP Family), 153- and 235-amino acid (27-kD) Homeobox C6 Protein isoforms are highly conserved sequence-specific DNA-binding homeobox transcription repressors that can cooperate with other HOX proteins and may contribute to the breast cell phenotype through co-operative interactions. As part of a developmental regulatory system that provides anterior-posterior positional identity to cells, HOXC6 may regulate the coordinated expression of multiple genes involved in morphogenesis and differentiation. (from LocusLink, Swiss-Prot, OMIM, and NCI), Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development.] |
| Lactobacillus frumenti | NCBITaxon_104955 |