Terminology Service for NFDI4Health
All terms in EFO
| Label | Id | Description |
|---|---|---|
| Leydig cell hypoplasia due to LHB deficiency | Orphanet_325448 | |
| Leydig cell hypoplasia | MONDO_0019155 | [A condition in males that affects sexual development. It is characterized by underdevelopment of the Leydig cells, which are cells in the testes that secrete male sex hormones (androgens) and are important for male sexual development. Individuals with LCH have a typical male genetic make-up (46, XY), but due to lowered levels of androgens, may have a range of genital (reproductive organ) differences. Individuals with LCH may have a small penis (micropenis),the opening of the urethra may be located on the underside of the penis (hypospadias), or the scrotum may be divided into two halves (bifid scrotum). Given these differences in development, the external genitalia may not appear clearly male or female (ambiguous genitalia). Some individuals with LCH can have female external genitalia and small testes that have not descended and are located in the pelvis, abdomen, or groin. This may be referred to as type 1, whereas less severe cases might be called type 2. LCH is inherited in an autosomal recessive manner and is caused by mutations in the LHCGR gene.Although there is no specific treatment or cure for LCH, there may be ways to manage the symptoms. A team of doctors or specialists is often needed to figure out the treatment options for each person.] |
| tomatidine | CHEBI_9629 | |
| 1-tetradecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine | CHEBI_86094 | [A phosphatidylcholine 32:2 in which the acyl groups specified at positions 1 and 2 are tetradecanoyl and (9Z,12Z)-octadecadienoyl respectively.] |
| dermatologic drug | CHEBI_50177 | [A drug used to treat or prevent skin disorders or for the routine care of skin.] |
| response to acetaminophen | GO_1901554 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaminophen stimulus. acetaminophen is a non narcotic analgesic, a non steroidal anti inflammatory and an anti pyretic.] |
| response to paclitaxel | GO_1901555 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel, an antineoplastic agent derived from yew. Ref CHEBI:45863.] |
| response to antimicrotubule agent | EFO_0005260 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimicrotubule agent stimulus.] |
| response to candesartan | GO_1901556 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus. Candesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. CHEBI:3347] |
| response to fenofibrate | GO_1901557 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus. Fenofibrates are a class of fibrate drugs which is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. Like other fibrates, it reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high-density lipoprotein (HDL) levels and reducing triglycerides level. It is used alone or in conjunction with statins in the treatment of hypercholesterolemia and hypertriglyceridemia. CHEBI:5001] |
| response to metformin | GO_1901558 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus. Metformin is an oral antidiabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus. Metformin is an oral antidiabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function.] |
| metformin | CHEBI_6801 | [A guanidine that has formula C4H11N5.] |
| response to ribavirin | GO_1901559 | [Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stilumulus. Ribavirin is a drug used to treat hepatis C and other viral diseases.] |
| tomatine | CHEBI_9630 | |
| motexafin gadolinium | CHEBI_50161 | [A metallotexaphyrin that has formula C52H72GdN5O14.] |
| capillary | UBERON_0001982 | [Any of the smallest blood vessels connecting arterioles with venules.] |
| lung blood vessel | UBERON_0003512 | [A blood vessel that is part of a lung [Automatically generated definition].] |
| alveolar sac | UBERON_0002169 | [The small terminal dilation of the alveolar ducts around which the alveoli form pocket-like clusters.] |
| obsolete_slow muscle cell somite 7 | EFO_0003600 | |
| obsolete_lateral wall spinal cord | EFO_0003602 |