Terminology Service < Semantic Lookup Platform

All terms in GO

Label	Id	Description
DNA negative supercoiling activity	GO_0034335	[Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.]
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	GO_0003918	[Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.]
ATP-independent chaperone mediated protein folding	GO_1990507	[The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and independent of ATP hydrolysis.]
chaperone-mediated protein folding	GO_0061077	[The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.]
CKM complex	GO_1990508	[Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8.]
nuclear cyclin-dependent protein kinase holoenzyme complex	GO_0019908	[Cyclin-dependent protein kinase (CDK) complex found in the nucleus.]
cell cycle DNA replication maintenance of fidelity	GO_1902298	[Any maintenance of fidelity that is involved in cell cycle DNA replication.]
mitotic DNA replication	GO_1902969	[Any nuclear DNA replication that is involved in a mitotic cell cycle.]
negative regulation of ion transmembrane transporter activity	GO_0032413	[Any process that stops or reduces the activity of an ion transporter.]
mitotic DNA-dependent DNA replication	GO_1990506	[A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.]
dendritic lamellar body	GO_1990503	[A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions.]
lamellar body	GO_0042599	[A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.]
dense core granule exocytosis	GO_1990504	[The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.]
calcium-ion regulated exocytosis	GO_0017156	[The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.]
exon-exon junction complex	GO_0035145	[A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.]
ATPase inhibitor complex	GO_1903503	[A protein complex which is capable of ATPase inhibitor activity.]
dense core granule maturation	GO_1990502	[Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.]
secretory granule maturation	GO_0061792	[Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling.]
eif4e-cup complex	GO_1990500	[A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.]
translation repressor complex	GO_1903502	[A protein complex which is capable of translation repressor activity.]