Terminology Service < Semantic Lookup Platform

All terms in GO

Label	Id	Description
coenzyme binding	GO_0050662	[Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.]
anion binding	GO_0043168	[Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge.]
voltage-gated proton channel activity	GO_0030171	[Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.]
proton channel activity	GO_0015252	[Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.]
obsolete calpain inhibitor activity	GO_0030161	[OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue.]
regulation of proteolysis	GO_0030162	[Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.]
regulation of protein metabolic process	GO_0051246	[Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.]
proteolysis	GO_0006508	[The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.]
protein catabolic process	GO_0030163	[The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.]
macromolecule catabolic process	GO_0009057	[The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.]
protein metabolic process	GO_0019538	[The chemical reactions and pathways involving a protein. Includes protein modification.]
protein denaturation	GO_0030164	[Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.]
cellular protein catabolic process	GO_0044257	[The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.]
PDZ domain binding	GO_0030165	[Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.]
proteoglycan biosynthetic process	GO_0030166	[The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.]
glycoprotein biosynthetic process	GO_0009101	[The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.]
glycoprotein catabolic process	GO_0006516	[The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.]
platelet activation	GO_0030168	[A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.]
cell activation	GO_0001775	[A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.]
blood coagulation	GO_0007596	[The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.]