Terminology Service < Semantic Lookup Platform

All terms in GO

Label	Id	Description
Lewy neurite	GO_0097462	[Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.]
gemmule	GO_0097463	[Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex.]
thorny excrescence	GO_0097464	[Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.]
somatic spine	GO_0097465	[Spine emanating from the cell soma of a neuron.]
ubiquitin-dependent glycoprotein ERAD pathway	GO_0097466	[An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.]
response to glycoprotein	GO_1904587	[Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.]
ubiquitin-dependent ERAD pathway	GO_0030433	[The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.]
type III terminal bouton	GO_0097467	[Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones.]
cell death in response to oxidative stress	GO_0036473	[Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus.]
obsolete cyclin-dependent protein tyrosine kinase activity	GO_0097469	[OBSOLETE. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. This reaction requires the binding of a regulatory cyclin subunit.]
Wnt signalosome	GO_1990909	[A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein.]
beta-catenin-TCF complex	GO_1990907	[A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.]
obsolete Lys63-specific zinc metallopeptidase deubiquitinase activity	GO_1990908	[OBSOLETE. Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein by a mechanism where zinc acts as the nucleophile.]
dinoflagellate peduncle	GO_1990905	[A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).]
accessory outer segment	GO_1990906	[A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors.]
ribbon synapse	GO_0097470	[Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.]
synapse	GO_0045202	[The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.]
synaptic ribbon	GO_0098681	[A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical.]
GO_1990903	GO_1990903
mossy fiber rosette	GO_0097471	[A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes.]