Terminology Service < Semantic Lookup Platform

All terms in GO

Label	Id	Description
bubble DNA binding	GO_0000405	[Interacting selectively and non-covalently with DNA that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA.]
DNA secondary structure binding	GO_0000217	[Interacting selectively and non-covalently with DNA containing secondary structure elements such as four-way junctions, bubbles, loops, Y-form DNA, or double-strand/single-strand junctions.]
double-strand/single-strand DNA junction binding	GO_0000406	[Interacting selectively and non-covalently with a region of DNA that contains double-stranded DNA flanked by a region of single-stranded DNA.]
Y-form DNA binding	GO_0000403	[Interacting selectively and non-covalently with segment of DNA shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.]
heteroduplex DNA loop binding	GO_0000404	[Interacting selectively and non-covalently with DNA containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration.]
DNA insertion or deletion binding	GO_0032135	[Interacting selectively and non-covalently with double-stranded DNA containing insertions or deletions.]
open form four-way junction DNA binding	GO_0000401	[Interacting selectively and non-covalently with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.]
four-way junction DNA binding	GO_0000400	[Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.]
regulation of isotype switching to IgG isotypes	GO_0048302	[Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.]
regulation of isotype switching	GO_0045191	[Any process that modulates the frequency, rate or extent of isotype switching.]
isotype switching to IgG isotypes	GO_0048291	[The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.]
crossed form four-way junction DNA binding	GO_0000402	[Interacting selectively and non-covalently with DNA containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands.]
negative regulation of isotype switching to IgG isotypes	GO_0048303	[Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes.]
negative regulation of isotype switching	GO_0045829	[Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.]
negative regulation of isotype switching to IgD isotypes	GO_0048300	[Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes.]
regulation of isotype switching to IgD isotypes	GO_0048299	[Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.]
isotype switching to IgD isotypes	GO_0048292	[The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.]
positive regulation of isotype switching to IgD isotypes	GO_0048301	[Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes.]
positive regulation of isotype switching	GO_0045830	[Any process that activates or increases the frequency, rate or extent of isotype switching.]
calcium-dependent protein binding	GO_0048306	[Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.]