Terminology Service < Semantic Lookup Platform

All terms in GO

Label	Id	Description
positive regulation of insulin receptor signaling pathway	GO_0046628	[Any process that increases the frequency, rate or extent of insulin receptor signaling.]
leptin receptor activity	GO_0038021	[Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.]
response to isoquinoline alkaloid	GO_0014072	[Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.]
IKKalpha-IKKalpha complex	GO_0038059	[A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits.]
BMP secretion	GO_0038055	[The controlled release of a member of the BMP family of proteins from a cell.]
signal release	GO_0023061	[The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.]
negative regulation of BMP signaling pathway by negative regulation of BMP secretion	GO_0038056	[Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell.]
negative regulation of BMP secretion	GO_2001285	[Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion.]
negative regulation of BMP signaling pathway	GO_0030514	[Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.]
TNFSF11 binding	GO_0038057	[Interacting selectively and non-covalently with tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.]
TNFSF11 receptor activity	GO_0038058	[Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function.]
TNFSF11-mediated signaling pathway	GO_0071847	[A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.]
GO_0038051	GO_0038051
GO_0038052	GO_0038052
obsolete transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding	GO_0038053	[OBSOLETE. Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements.]
G protein-coupled estrogen receptor activity	GO_0038054	[Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.]
nitric oxide-cGMP-mediated signaling pathway	GO_0038060	[Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP.]
dynorphin receptor activity	GO_0038048	[Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin.]
GO_0038049	GO_0038049
transforming growth factor-beta secretion	GO_0038044	[The regulated release of transforming growth factor-beta (TGF-beta) from a cell into the extracellular region. TGF-beta is mostly secreted as a large latent TGF-beta complex (LLC) containing latency-associated proteins (LAPs) derived from the N-terminal region of the TGF-beta gene product, dimeric TGF-beta and latent TGF-beta binding proteins (LTBPs).]