Terminology Service < Semantic Lookup Platform

All terms in GO

Label	Id	Description
Sar guanyl-nucleotide exchange factor activity	GO_0005090	[Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Sar family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.]
GTPase regulator activity	GO_0030695	[Modulates the rate of GTP hydrolysis by a GTPase.]
guanyl-nucleotide exchange factor adaptor activity	GO_0005091	[The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way.]
GDP-dissociation inhibitor activity	GO_0005092	[Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.]
GDP binding	GO_0019003	[Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.]
Rab GDP-dissociation inhibitor activity	GO_0005093	[Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding.]
Rho GDP-dissociation inhibitor activity	GO_0005094	[Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.]
obsolete FK506-sensitive peptidyl-prolyl cis-trans isomerase	GO_0030051	[OBSOLETE. Interacts selectively with the immunosuppressant FK506, and possesses peptidyl-prolyl isomerase activity (catalysis of the reaction: peptidoproline (omega=180) = peptidylproline (omega=0)).]
GTPase inhibitor activity	GO_0005095	[Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.]
enzyme inhibitor activity	GO_0004857	[Binds to and stops, prevents or reduces the activity of an enzyme.]
GTPase activity	GO_0003924	[Catalysis of the reaction: GTP + H2O = GDP + phosphate.]
negative regulation of GTPase activity	GO_0034260	[Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.]
obsolete parvulin	GO_0030052	[OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin.]
GTPase activator activity	GO_0005096	[Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.]
positive regulation of GTPase activity	GO_0043547	[Any process that activates or increases the activity of a GTPase.]
obsolete immunophilin	GO_0030053	[OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin.]
GO_0005097	GO_0005097
cell junction	GO_0030054	[A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.]
GO_0005098	GO_0005098
cell-substrate junction	GO_0030055	[A cell junction that forms a connection between a cell and the extracellular matrix.]