Terminology Service < Semantic Lookup Platform

All terms in HP

Label	Id	Description
Reduced euglobulin clot lysis time	HP_0040247	[Abnormally decreased length of time required for an in vitro clot to dissolve in the absence of the normal plasmin inhibitors. This test is a clinical assay used to measure fibrinolysis. The euglobulin fraction of plasma is precipitated and used to form clot by addition of thrombin; after clot forms the rate of clot breakdown (fibrinolysis) can be monitored.]
Reduced plasminogen activator inhibitor 1 activity	HP_0040248	[Reduced activity of plasminogen activator inhibitor 1. This protein down-regulates fibrinolysis in the circulation by inhibiting the two major plasminogen activators: tissue-plasminogen activator and urokinase-plasminogen activator.]
Abnormal response to short acting pulmonary vasodilator	HP_0030893	[Pulmonary vasodilator testing is performed during right-heart catheterization and involves a short-acting vasoactive agent such as adenosine, epoprostenol, or inhaled nitric oxide. The current definition of a normal (positive) response is a drop in mean pulmonary artery pressure of at least 10 mm Hg (or 20 percent) to below 40 mm Hg.]
Insufficient response to short acting pulmonary vasodilator	HP_0030894	[No fall in mean pulmonary arterial pressure (mPAP) falls by at least 10 mmHg to an absolute value less than 40 mmHg without a degradation in cardiac output (CO) in response to a short-acting vasoactive agent such as adenosine, epoprostenol, or inhaled nitric oxide.]
Hyperintensity of cerebral white matter on MRI	HP_0030890	[A brighter than expected signal on magnetic resonance imaging emanating from the cerebral white matter.]
Deep cerebral white matter hyperdensities	HP_0030892	[Areas of brighter than expected signal on magnetic resonance imaging emanating from locations distant from the ventricular system.]
cobamides	CHEBI_23341
Abnormal circulating biopterin concentration	HP_0040210	[A deviation from the normal concentration of biopterin in the blood circulation.]
fistula	MPATH_70	[An abnormal passage between two internal organs or leading from a cavity to the body surface.]
unsaturated fatty acid anion	CHEBI_2580	[Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety.]
prostanoid	CHEBI_26347	[The family of natural prostaglandins and prostaglandin-like compounds including prostacyclins and thromboxanes.]
Hypoinsulinemia	HP_0040216	[A decreased concentration of insulin in the blood.]
Elevated hemoglobin A1c	HP_0040217	[An increased concentration of hemoglobin A1c (HbA1c), which is the product of nonenzymatic attachment of a hexose molecule to the N-terminal amino acid of the hemoglobin molecule. This reaction is dependent on blood glucose concentration, and therefore reflects the mean glucose concentration over the previous 8 to 12 weeks. The HbA1c level provides a better indication of long-term glycemic control than one-time blood or urinary glucose measurements.]
Reduced natural killer cell count	HP_0040218	[Less than normal number of natural killer cells, a type of lymphocyte in the innate immune system with an ability to mediate cytotoxicity and produce cytokines after the ligation of a germline-encoded activation receptor.]
Absent natural killer cells	HP_0040219	[Lack of natural killer cells, a type of lymphocyte in the innate immune system that contains cytoplasmic granzymes, i.e., small granules with perforin and proteases that allow natural killer cells to form pores in the cell membrane of the target cell through which the granzymes and associated molecules can enter, inducing apoptosis.]
Risus sardonicus	HP_0040212	[Fixed sarcastic grimace and anxious expression. Caused by spasms of the masseter and other facial muscles.]
Hypopnea	HP_0040213	[Hypopnea is referring to breathing that is abnormally shallower and/or slow.]
Abnormal insulin level	HP_0040214	[An abnormal concentration of insulin in the body.]
non-covalently-bound molecular entity	CHEBI_50967	[Systems consisting of two or more molecular entities held together by non-covalent interactions.]
diverticulum	MPATH_68	[A blind ended outpouching through the wall of a tubular organ or bounded cavity.]