Terminology Service < Semantic Lookup Platform

All terms in MESH

Label	Id	Description
Human Genome Project	D016045	[A coordinated effort of researchers to map (CHROMOSOME MAPPING) and sequence (SEQUENCE ANALYSIS, DNA) the human GENOME., A coordinated effort to document the genetic variation of the human species worldwide.]
Genetic Research	D036281	[Research into the cause, transmission, amelioration, elimination, or enhancement of inherited disorders and traits.]
Genomics	D023281	[The systematic study of the complete DNA sequences (GENOME) of organisms.]
Information Services	D007255	[Organized services to provide information on any questions an individual might have using databases and other sources. (From Random House Unabridged Dictionary, 2d ed)]
Human Genetics	D000074705	[The scientific study of inherited human variation.]
Zalcitabine	D016047	[A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.]
Dideoxynucleosides	D015224	[Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.]
Dideoxyadenosine	D016048	[A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is an inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal side effect is nephrotoxicity. In vivo, dideoxyadenosine is rapidly metabolized to DIDANOSINE (ddI) by enzymatic deamination; ddI is then converted to dideoxyinosine monophosphate and ultimately to dideoxyadenosine triphosphate, the putative active metabolite.]
Deoxyadenosines	D003839	[Adenosine molecules which can be substituted in any position, but are lacking one hydroxyl group in the ribose part of the molecule.]
Didanosine	D016049	[A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.]
Inosine	D007288	[A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)]
Zinc Deficiency, Neonatal, due to Low Breast Milk Zinc	C564286
Dystonia 18	C564288
Optical Phenomena	D055620	[LIGHT, its processes and properties, and the characteristics of materials interacting with it.]
Physical Phenomena	D055585	[The entities of matter and energy, and the processes, principles, properties, and relationships describing their nature and interactions.]
Orbital Myositis	D055622	[Inflammation of the extraocular muscle of the eye. It is characterized by swelling which can lead to ischemia, fibrosis, or ORBITAL PSEUDOTUMOR.]
Myositis	D009220	[Inflammation of a muscle or muscle tissue.]
Orbital Diseases	D009916	[Diseases of the bony orbit and contents except the eyeball.]
Keratosis, Actinic	D055623	[White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA.]
Keratosis	D007642	[Any horny growth such as a wart or callus.]