Terminology Service < Semantic Lookup Platform

All terms in MESH

Label	Id	Description
Neutral Ceramidase	D055576	[A ceramidase subtype that is active at neutral pH. It is found at high levels within the SMALL INTESTINE and in the BRAIN.]
Ceramidases	D055572	[Amidohydrolases that are specific for the cleavage of the N-acyl linkage of CERAMIDES. Ceramidases are classified as acidic, neutral or basic according to the optimal pH with which they function.]
Farber Lipogranulomatosis	D055577	[A sphingolipidosis subtype that is characterized by the histological appearance of granulomatous deposits in tissues. It results from the accumulation of CERAMIDES in various tissues due to an inherited deficiency of ACID CERAMIDASE.]
Sphingolipidoses	D013106	[A group of inherited metabolic disorders characterized by the intralysosomal accumulation of SPHINGOLIPIDS primarily in the CENTRAL NERVOUS SYSTEM and to a variable degree in the visceral organs. They are classified by the enzyme defect in the degradation pathway and the substrate accumulation (or storage). Clinical features vary in subtypes but neurodegeneration is a common sign.]
3,3',5,5'-tetra-tert-butyl-4,4'-bisphenol	C118326
3-bromotyrosine	C118327
aps1 protein, S pombe	C118328
Microphthalmia with Cyst, Bilateral Facial Clefts, and Limb Anomalies	C564370
OAT-K2 protein, rat	C118329
Brain Small Vessel Disease with Hemorrhage	C564372
Secretory Pathway	D055571	[A series of sequential intracellular steps involved in the transport of proteins (such as hormones and enzymes) from the site of synthesis to outside the cell. The pathway involves membrane-bound compartments through which the newly synthesized proteins undergo POST-TRANSLATIONAL MODIFICATIONS, packaging, storage, or transportation to the PLASMA MEMBRANE for secretion.]
Exocytosis	D005089	[Cellular release of material within membrane-limited vesicles by fusion of the vesicles with the CELL MEMBRANE.]
Biological Transport	D001692	[The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.]
Amidohydrolases	D000581
Acid Ceramidase	D055573	[A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.]
Alkaline Ceramidase	D055574	[A ceramidase subtype that is active at alkaline pH. It is found at high levels within the SMALL INTESTINE.]
Neuronopathy, Distal Hereditary Motor, Type Viib	C564362
Ichthyosis, Leukocyte Vacuoles, Alopecia, And Sclerosing Cholangitis	C564365
N-chloromethylbrucine	C118330
Niemann-Pick Disease, Type F	C564366