Terminology Service < Semantic Lookup Platform

All terms in MESH

Label	Id	Description
Cholestanones	D002778	[CHOLESTANES substituted with any number of keto groups.]
Cholestasis	D002779	[Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).]
Liver Diseases	D008107	[Pathological processes of the LIVER.]
Cholesteatoma	D002781	[A non-neoplastic mass of keratin-producing squamous EPITHELIUM, frequently occurring in the MENINGES; bones of the skull, and most commonly in the MIDDLE EAR and MASTOID region. Cholesteatoma can be congenital or acquired. Cholesteatoma is not a tumor nor is it associated with high CHOLESTEROL.]
Cholestenones	D002783	[CHOLESTENES with one or more double bonds and substituted by any number of keto groups.]
Cholesterol	D002784	[The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.]
Sterol O-Acyltransferase	D002785	[An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This enzyme has been found in the adrenal gland, gonads, liver, intestinal mucosa, and aorta of many mammalian species. EC 2.3.1.26.]
Cholesterol Side-Chain Cleavage Enzyme	D002786	[A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.]
Cytochrome P450 Family 11	D000072476	[A cytochrome P450 enzyme family whose members localize to the INNER MITOCHONDRIAL MEMBRANE where they function in the biosynthesis of STEROIDS.]
Steroid Hydroxylases	D013250	[Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthesis and metabolism.]
Sterol Esterase	D002787	[An enzyme that catalyzes the hydrolysis of CHOLESTEROL ESTERS and some other sterol esters, to liberate cholesterol plus a fatty acid anion.]
Cholesterol Esters	D002788	[Fatty acid esters of cholesterol which constitute about two-thirds of the cholesterol in the plasma. The accumulation of cholesterol esters in the arterial intima is a characteristic feature of atherosclerosis.]
Cholesterol Oxidase	D002789	[An enzyme that catalyzes the oxidation of cholesterol in the presence of molecular oxygen to 4-cholesten-3-one and hydrogen peroxide. The enzyme is not specific for cholesterol, but will also oxidize other 3-hydroxysteroids. EC 1.1.3.6.]
3-Hydroxysteroid Dehydrogenases	D015096	[Catalyze the oxidation of 3-hydroxysteroids to 3-ketosteroids.]
Cholesterol 7-alpha-Hydroxylase	D002790	[A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.]
Cytochrome P450 Family 7	D000072474	[A cytochrome P450 enzyme family whose members function as steroid 7-alpha hydroxylases.]
Cholesterol, Dietary	D002791	[Cholesterol present in food, especially in animal products.]
Cholestyramine Resin	D002792	[A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion.]
Polystyrenes	D011137	[Polymerized forms of styrene used as a biocompatible material, especially in dentistry. They are thermoplastic and are used as insulators, for injection molding and casting, as sheets, plates, rods, rigid forms and beads.]
Cholic Acids	D002793	[The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.]