Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Fluorotestosterone	NCIT_C29043	[A synthetic nonaromatizable androgen analog of testosterone. Fluorotestosterone (6 alpha-fluorotestosterone) binds to and activates specific nuclear receptors inhibits and is equipotent to testosterone. (NCI04)]
Protection of Telomeres Protein 1	NCIT_C107657	[Protection of telomeres protein 1 (634 aa, ~71 kDa) is encoded by the human POT1 gene. This protein plays a role in telomere maintenance.]
DNA Binding Protein	NCIT_C16518	[Proteins that non-covalently interact with deoxyribonucleic acid as a result of intermolecular physical forces and spatial complementarity. Many genetic regulatory DNA binding proteins bind to double- or single-stranded DNA in a sequence-specific manner and share common structural motifs such as the zinc-finger, helix-turn-helix, and leucine zipper.]
HAQ-DI Without VAS - Special Aid (Hygiene or Reach or Grip or Act)	NCIT_C132613	[Health Assessment Questionnaire Disability Index Without Pain Visual Analog Scale (HAQ-DI Without VAS) Aids or devices that you usually use for any of these activities: Other (specify) - for hygiene, reach, grip and activities.]
Gastrointestinal Stromal Tumor of Uncertain Malignant Potential	NCIT_C54000	[A gastrointestinal stromal tumor that is characterized by a maximum diameter greater than 5 cm and equal or less than 10 cm (gastric localization), or greater than 2 cm and equal or less than 5 cm (intestinal localization) and no more than 5 mitotic figures per 50 high power fields.]
Famciclovir	NCIT_C29044	[A diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04)]
CNOT3 Gene	NCIT_C107658	[This gene is involved in mRNA degradation, miRNA-mediated repression, translational regulation and general transcription regulation.]
HAQ-DI Without VAS - Help: Hygiene	NCIT_C132614	[Health Assessment Questionnaire Disability Index Without Pain Visual Analog Scale (HAQ-DI Without VAS) Usually need help from another person: Hygiene.]
Neoplastic Spindle Stromal Cell	NCIT_C54001
Famotidine	NCIT_C29045	[A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.]
CNOT3 wt Allele	NCIT_C107659	[Human CNOT3 wild-type allele is located in the vicinity of 19q13.4 and is approximately 18 kb in length. This allele, which encodes CCR4-NOT transcription complex subunit 3 protein, plays a role in RNA processing, translational regulation and transcriptional regulation.]
RNA Degradation Pathway	NCIT_C91512
HAQ-DI Without VAS - Help: Reach	NCIT_C132615	[Health Assessment Questionnaire Disability Index Without Pain Visual Analog Scale (HAQ-DI Without VAS) Usually need help from another person: Reach.]
Neoplastic Epithelioid Stromal Cell	NCIT_C54002
Felodipine	NCIT_C29046	[A dihydropyridine calcium channel blocking agent. Felodipine inhibits the influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)]
HAQ-DI Without VAS - Help: Gripping and Opening Things	NCIT_C132616	[Health Assessment Questionnaire Disability Index Without Pain Visual Analog Scale (HAQ-DI Without VAS) Usually need help from another person: Gripping and opening things.]
Anaplastic Adrenal Cortex Carcinoma	NCIT_C68644	[An adrenal cortex carcinoma characterized by the presence of necrotic changes, hemorrhage, nuclear atypia, and mitotic activity.]
Fenofibrate	NCIT_C29047	[A synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. Fenofibrate is hydrolyzed in vivo to its active metabolite fenofibric acid that binds to and activates peroxisome proliferator activated receptor alpha (PPARalpha), resulting in the activation of lipoprotein lipase and reduction of the production of apoprotein C-III, an inhibitor of lipoprotein lipase activity. Increased lipolysis and a fall in plasma triglycerides, in turn, leads to the modification of the small, dense low density lipoporotein (LDL) particles into larger particles that are catabolized more rapidly due to a greater affinity for cholesterol receptors. In addition, activation of PPARalpha also increases the synthesis of apoproteins A-I, A-II, and high density lipoprotein (HDL)-cholesterol. Overall, fenofibrate reduces total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) while increasing HDL cholesterol.]
Fibrate Antilipidemic Agent	NCIT_C98150	[An antilipidemic agent derived from fibric acid that lowers serum LDL cholesterol levels by activating peroxisome proliferator activated receptor alpha (PPARa).]
Body Surface Area Formula	NCIT_C68645	[A mathematical formula for calculating the body surface area for an organism.]