Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
TSPAN32 Gene	NCIT_C20798	[This gene is associated with several disease entities, however an exact function has not been elucidated. The gene may play a role in malignancies and hematopoietic cell function.]
K-RAS ASP-12 Mutant Protein	NCIT_C29135	[A mutant form of the p21-ras protein transcribed from a mutant form of the oncogene K-ras. K-Ras is located in the plasma membrane and transduces growth and differentiation signals from activated receptors to protein kinases within the cell. K-RAS ASP-12 contains a mutation at codon 12 and may be used in cancer immunotherapy. (NCI04)]
CDKN2A NP_000068.1:p.A30V	NCIT_C146928	[A change in the amino acid residue at position 30 in the cyclin-dependent kinase inhibitor 2 protein where alanine has been replaced by valine.]
CDKN2A NM_000077.4:c.89C>T	NCIT_C146927	[A nucleotide substitution at position 89 of the coding sequence of the CDKN2A gene where cytosine has been mutated to thymine.]
7p13-p11.1	NCIT_C68733	[A chromosome band present on 7p]
7p	NCIT_C13561	[Proximal (short) arm of chromosome 7]
ARID4B Gene	NCIT_C20799	[This gene plays a role in co-repression and is a molecular marker for a range of malignancies.]
K-RAS ASP-13 Mutant Protein	NCIT_C29136	[A synthetic form of the ras protein containing a point mutation at position 13 (glycine to asparagine). Vaccines using mutant K-ras proteins may be used in the immunotherapy of various cancers that express mutated K-ras proteins. (NCI04)]
CDKN2A NM_000077.4:c.152T>A	NCIT_C146929	[A nucleotide substitution at position 152 of the coding sequence of the CDKN2A gene where thymine has been mutated to adenine.]
CDKN2A NP_000068.1:p.V51D	NCIT_C146930	[A change in the amino acid residue at position 51 in the cyclin-dependent kinase inhibitor 2 protein where valine has been replaced by aspartic acid.]
H4C9 Gene	NCIT_C68734	[This gene plays a role in nucleosomal structure.]
Histone H4 Gene	NCIT_C154303	[A gene encoding the core histone protein histone H4.]
K-RAS GLY-12 Mutant Protein	NCIT_C29137	[A synthetic form of the K-ras protein containing any one of a number of point mutations at position 12 which is normally occupied by glycine (GLY). Vaccines using mutant K-ras proteins may be used in the immunotherapy of various cancers that express mutated K-ras proteins. (NCI04)]
H4C9 wt Allele	NCIT_C68735	[Human H4C9 wild-type allele is located in the vicinity of 6p21.33 and is approximately 2 kb in length. This allele, which encodes histone H4 protein, is involved in the modulation of the structure of chromatin. In B cell non-Hodgkin lymphoma this gene can be involved in a translocation t(3;6)(q27;p21) that fuses it to the enhancer region of the BCL6 gene.]
K-RAS VAL-12 Mutant Protein	NCIT_C29138	[A synthetic form of the K-ras protein containing a point mutation at position 12 (glycine to valine). Vaccines using mutant K-ras proteins may be used in the immunotherapy of various cancers that express mutated K-ras proteins. (NCI04)]
IL21R Gene	NCIT_C68736	[This gene is involved in cytokine recognition.]
mRNA Export	NCIT_C19424	[Transport of messenger RNA from its nuclear site of transcription to the cytoplasm, where the message is translated into protein by ribosomes.]
Hydroxypropylcellulose	NCIT_C29139
IL21R wt Allele	NCIT_C68737	[Human IL21R wild-type allele is located in the vicinity of 16p11 and is approximately 48 kb in length. This allele, which encodes interleukin-21 receptor protein, is involved in the regulation of cytokine signaling. A translocation t(3;7)(q27;p12) that fuses the gene to the BCL6 gene is implicated in diffuse large B-cell lymphomas.]
Cytokine-Cytokine Receptor Signaling Pathway	NCIT_C91469