Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Gliosarcoma	NCIT_C3796	[A rare histological variant of glioblastoma (WHO grade IV) characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation (WHO).]
TP53 NM_000546.5:c.818G>T	NCIT_C146919	[A nucleotide substitution at position 818 of the coding sequence of the TP53 gene where guanine has been mutated to thymine.]
TP53 NP_000537.3:p.R273L	NCIT_C146920	[A change in the amino acid residue at position 273 in the cellular tumor antigen p53 protein where arginine has been replaced by leucine.]
Laetrile	NCIT_C29149	[Originally, the name laetrile was the contraction of laevo-mandelonitrile glucoside, a cyanogenic glycoside found naturally in some plants. Over the years the meaning of laetrile has changed. There are now preparations called Laetrile where amygdalin is the major constituent. Laetrile and amygdalin are often used interchangeably, but are different agents. Cyanide and benzaldehyde are metabolites of both laetrile and amygdalin. Both metabolites may possess antineoplastic properties. Laetrile has been used as an anticancer treatment in humans worldwide, but scientific evidence does not support its effectiveness. It is not approved for use in the United States. (NCI04)]
Adult Giant Cell Glioblastoma	NCIT_C68702	[A giant cell glioblastoma occurring in adults.]
Giant Cell Glioblastoma	NCIT_C4325	[A rare histological variant of glioblastoma (WHO grade IV) with a predominance of bizarre, multinucleated giant cells, an occasionally abundant stromal reticulin network, and a high frequency of TP53 mutations. (WHO)]
Adult Supratentorial Embryonal Tumor, Not Otherwise Specified	NCIT_C68703	[A supratentorial embryonal tumor, not otherwise specified that occurs in adults.]
Adult Central Nervous System Embryonal Tumor, Not Otherwise Specified	NCIT_C5411	[A central nervous system embryonal tumor, not otherwise specified that occurs in adults.]
Malignant Adult Brain Neoplasm	NCIT_C5115	[A malignant brain neoplasm occurring in adults.]
Supratentorial Embryonal Tumor, Not Otherwise Specified	NCIT_C6968	[A central nervous system embryonal tumor, not otherwise specified arising from the supratentorial region.]
Cancer Stem Cell	NCIT_C68706	[A malignant cell which may derive from mutations in normal stem cells. Cancer stem cells proliferate and give rise to other malignant cells. They may be present in very small numbers in the tumor and may not be present in all tumors. Many investigators believe that cancer stem cells cause relapse of the tumor and that novel cancer therapies should specifically target those cells.]
TP53 NM_000546.5:c.844C>T	NCIT_C146921	[A nucleotide substitution at position 844 of the coding sequence of the TP53 gene where cytosine has been mutated to thymine.]
TP53 NP_000537.3:p.R282W	NCIT_C146923	[A change in the amino acid residue at position 282 in the cellular tumor antigen p53 protein where arginine has been replaced by tryptophan.]
TP53 NM_000546.5:c.843_844delCCinsTT	NCIT_C146922	[A complex substitution where the nucleotide sequence at positions 843 and 844 of the coding sequence of the TP53 gene has changed from cytosine-cytosine to thymine-thymine.]
TP53 NM_000546.5:c.844C>G	NCIT_C146924	[A nucleotide substitution at position 844 of the coding sequence of the TP53 gene where cytosine has been mutated to guanine.]
TP53 NP_000537.3:p.R282G	NCIT_C146925	[A change in the amino acid residue at position 282 in the cellular tumor antigen p53 protein where arginine has been replaced by glycine.]
CDKN2A Gene Product	NCIT_C129948	[A protein encoded by the CDKN2A gene.]
Pomegranate Seed Oil	NCIT_C107350	[The oil extracted from the seeds of Punica granatum. Pomegranite seed oil is a source of antioxidants and is used in skincare preparations.]
Pumpkin Seed Oil	NCIT_C107351	[The oil extracted from the seeds of Cucurbita pepo var. styriaca. Pumpkin seed oil is used primarily as a food flavoring.]
Rhododendron dauricum Leaf Oil	NCIT_C107352	[The essential oil of Rhododendron dauricum.]