Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Paraneoplastic Disease Antigen Gene	NCIT_C20817
RAD51 Family Gene	NCIT_C20813	[The RAD51 family of related genes, identified in both yeast and humans, encode strand-transfer proteins thought to be involved in recombinational repair of DNA damage and in meiotic recombination. Several members of the mammalian RAD51 gene family have been identified, for example, RAD51A, RAD51B, XRCC3, DMC1, and RAD51C. (From OMIM 602774)]
RAD51C Gene	NCIT_C20814	[This gene plays a role in DNA repair and meiotic recombination.]
Meiotic Recombination	NCIT_C21542	[Any type of homology-dependent DNA strand exchange occurring during gametogenesis and involving synapsis of parental homologs, strand breakage and exchange of segments to yield unique combinations of genes in the gamete. Disruptions in this process may result in aneuploidy of the resulting gametes, infertility in affected patients and trisomy in progeny.]
NOVA1 Gene	NCIT_C20815	[This gene is involved in neuronal synaptic activity and RNA interactions.]
Paraneoplastic Syndrome	NCIT_C3311	[A classification for rare disorders of diverse organ systems (endocrine, neuromuscular, gastrointestinal, renal, dermatologic, rheumatologic, hematologic) that are affected by substances secreted by a distant neoplasm but not by the action of the neoplasm itself metastasizing to that organ or tissue. Less than 1 % of neoplasms are associated with these syndromes. An immune-mediated response to neoplasm-elaborated proteins may be the cause of these syndromes. Additionally, their manifestation may signal the presence of an occult neoplasm, potentially at an earlier stage of disease thereby leading to a better clinical outcome. Constitutional signs may include fever, night sweats, anorexia and cachexia. Clinical course is usually progressive. Prognosis is variable depending on the effective treatment of the underlying neoplasm.]
TXN Gene	NCIT_C20816	[This gene plays a role in intercellular signaling, signal transduction and protection against cellular oxidative stress.]
Platelet Basic Protein	NCIT_C20810	[Platelet basic protein (128 aa, ~14 kDa) is encoded by the human PPBP gene. This protein is involved in platelet activation, chemotaxis, cytokine receptor binding and anti-bacterial activity.]
PPBP Gene Product	NCIT_C105903	[A protein encoded by the PPBP gene.]
Platelet Factor 4	NCIT_C20811	[Platelet factor 4 (101 aa, ~11 kDa) is encoded by the human PF4 gene. This protein is involved in the negative regulation of endothelial cell proliferation, the chemotaxis of neutrophils and monocytes and the positive regulation of blood coagulation.]
Coagulation Process	NCIT_C20812	[The process of clot formation.]
Paranasal Sinus Epithelium	NCIT_C54281
Paranasal Sinus	NCIT_C12763	[Any one of the air-filled spaces within the ethmoid, frontal, maxillary, or sphenoid bones, which communicate with the nasal cavity.]
Extrahepatic Bile Duct Adenocarcinoma	NCIT_C7975	[An adenocarcinoma arising from the epithelium of the extrahepatic bile ducts. Signs and symptoms include abdominal pain, anorexia, jaundice, pruritus, nausea and vomiting, and weight loss.]
Bile Duct Adenocarcinoma	NCIT_C27813	[An adenocarcinoma that arises from the intrahepatic bile ducts, the hepatic ducts, or the extrahepatic bile ducts. Adenocarcinomas that arise from the intrahepatic bile ducts or the hepatic ducts are called cholangiocarcinomas.]
Rhinorrhea	NCIT_C54282	[A discharge of fluid from the nose.]
Respiratory System Signs and Symptoms	NCIT_C85403
Distal 1/3 of the Common Bile Duct Adenocarcinoma	NCIT_C7976	[An adenocarcinoma that arises from the distal third of the common bile duct.]
Pancreatic Acinar Cell Carcinoma	NCIT_C7977	[An adenocarcinoma arising from the pancreas. It is characterized by the presence of relatively uniform malignant cells which form acinar patterns. It usually occurs during adulthood. Signs and symptoms include abdominal pain, weight loss, nausea, and diarrhea. It may metastasize to regional lymph nodes and the liver. A minority of patients develop lipase hypersecretion syndrome. This syndrome may be seen in patients with liver metastases and it is characterized by excessive secretion of lipase in the serum, polyarthralgia, and subcutaneous fat necrosis.]
Pancreatic Acinar Cell Neoplasm	NCIT_C95542	[An epithelial neoplasm that arises from the exocrine pancreas. It is characterized by the presence of neoplastic cells that resemble acinar cells and produce pancreatic exocrine enzymes. The vast majority are carcinomas.]