Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Taxonomic Identification Below Species Level	NCIT_C132419	[The determination of the taxonomic ranking of the microorganism that is below species level.]
Calcitroic Acid	NCIT_C107440	[A metabolite of calcidiol that is produced by 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1).]
SULT1A1 Gene	NCIT_C107441	[This gene is involved in the metabolism of catecholamines, phenolic drugs and neurotransmitters.]
SULT1A1 wt Allele	NCIT_C107442	[Human SULT1A1 wild-type allele is located in the vicinity of 16p12.1 and is approximately 18 kb in length. This allele, which encodes sulfotransferase 1A1 protein, plays a role in the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters.]
Sulfotransferase 1A1	NCIT_C107443	[Sulfotransferase 1A1 (295 aa, ~34 kDa) is encoded by the human SULT1A1 gene. This protein is involved in the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters.]
Sulfotransferase	NCIT_C17171	[Enzymes that catalyze the transfer of a sulfate group from 3'-phosphoadenylyl sulfate (active sulfate) to the hydroxyl group of an acceptor, which produces the sulfated derivative and 3'-phosphoadenosine 5'-phosphate. The enzymes are also involved in both the posttranslational sulfation of proteins and sulfate conjugation of exogenous chemicals and bile acids.]
Faraday	NCIT_C68828	[A constant used also as a unit of electric charge representing the electric charge carried by one mole (an Avogadro's number) of electrons or one equivalent of ions, and equal to the quantity of electricity that is capable of depositing or liberating one gram equivalent weight of a substance in electrolysis, approximately 9.6494E4 coulombs.]
ELAV-Like Protein 1	NCIT_C107477	[ELAV-like protein 1 (326 aa, ~36 kDa) is encoded by the human ELAVL1 gene. This protein plays a role in the regulation of gene expression by stabilizing AU-rich element-containing mRNAs.]
ELAVL1 Gene	NCIT_C107475	[This gene plays a role in the regulation of gene expression.]
Isometheptene/Dichloralphenazone/Acetaminophen	NCIT_C29260	[A combination preparation containing isometheptane, dichloralphenazone and acetaminophen with analgesic activity. Isometheptene is an indirect-acting sympathomimetic agent with vasoconstricting activity, thereby reducing the pulsation in cerebral arteries by constricting dilated cerebral blood vessels. Dichloralphenazone, a complex of chloral hydrate, which possesses hypnotic and sedative activity, and antipyrine, a pyrazolone analgesic and an antipyretic. Acetaminophen inhibits prostaglandin synthesis, thereby exerting analgesic activity. This preparation is used for the relief of migraine and tension headaches.]
Header	NCIT_C68829	[A line of text serving to indicate what the passage below it is about.]
Prolactin-Producing Pituitary Gland Neoplasm	NCIT_C7910	[An adenoma or carcinoma of the anterior lobe of the pituitary gland that produces prolactin.]
KRAS NP_004976.2:p.Q61X	NCIT_C107478	[A change in the amino acid residue at position 61 in the GTPase KRas protein where glutamine has been replaced by another amino acid.]
KRAS Protein Variant	NCIT_C98362	[A variation in the amino acid sequence for the GTPase KRas protein.]
KRAS Exon 3 Mutation	NCIT_C135716	[A molecular genetic abnormality indicating the presence of a mutation in exon 3 of the KRAS gene.]
Milk Thistle	NCIT_C29261	[A substance derived from any of several Old World coarse prickly-leaved shrubs and subshrubs including the plant Silybum marianum. Milk thistle's active chemical component is silymarin, which is a combination of flavonoids such as silibinin, dehydrosilibinin, silychristin and silydianin. These compounds are antioxidants and may alter the membrane structure of the liver cell, thereby blocking the absorption of toxins; they may also stimulate the production of new liver cells. In addition, milk thistle may increase cellular adenosine triphosphate (ATP) levels, exhibiting dose-dependent cardiac myocyte cytoprotection against doxorubicin. The silibinin component of milk thistle has been shown to inhibit growth factor receptor-mediated mitogenic and cell survival signaling, thereby inhibiting tumor growth. (NCI04)]
Plant-based Natural Product	NCIT_C106104	[Any mixture of substances or products derived from a plant or from part of a plant.]
KRAS NP_004976.2:p.A146X	NCIT_C107479	[A change in the amino acid residue at position 146 in the GTPase KRas protein where alanine has been replaced by another amino acid.]
KRAS Exon 4 Mutation	NCIT_C135717	[A molecular genetic abnormality indicating the presence of a mutation in exon 4 of the KRAS gene.]
Magnesium Hydroxide	NCIT_C29262	[A solution of magnesium hydroxide with antacid and laxative properties. Milk of magnesium exerts its antacid activity in low doses such that all hydroxide ions that enter the stomach are used to neutralize stomach acid. This agent exerts its laxative effect in higher doses so that hydroxide ions are able to move from the stomach to the intestines where they attract and retain water, thereby increasing intestinal movement (peristalsis) and inducing the urge to defecate.]