Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Left Lung, Superior Lobe, Superior Lingular Segment	NCIT_C132401	[The superior inguinal segment of the superior lobe of the left lung.]
Mycophenolate	NCIT_C29272	[The morpholinoethyl ester of mycophenolic acid (MPA). As an immunosuppressive agent in vivo, the active metabolite mycophenolate reversibly inhibits inosine 5'-monophosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanine nucleotides, thereby retarding T-cell and B-cell proliferation. MPA displays high lymphocyte specificity and cytotoxicity because lymphocyte metabolism is highly dependent on both salvage and de novo synthesis of guanine nucleotides. (NCI04)]
New York Heart Association Class III/IV	NCIT_C7922	[The two most severe classes of cardiac dysfunction according to a classification system developed by the New York Heart Association to grade cardiovascular function and disability. These classes are defined as follows: Class III - patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV - patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest.]
New York Heart Association Class	NCIT_C66909	[A finding associated with a patient based on the functional classification developed by the New York Heart Association (NYHA), for categorizing patients with defined or presumed cardiac disease. The classification system is based on the ability, or lack thereof, to engage in physical activity. The classification system comprises four classes, though NYHA Class III and Class IV are often aggregated for the purpose of outcomes analysis.]
Proton-Coupled Folate Transporter	NCIT_C107468	[Proton-coupled folate transporter (459 aa, ~50 kDa) is encoded by the human SLC46A1 gene. This protein plays a role in folate and antifolate transport across the plasma membrane, and heme transport in duodenal enterocytes.]
Right Lung, Inferior Lobe, Anterior Basal Segment	NCIT_C132402	[The anterior basal segment of the inferior lobe of the right lung.]
Aluminum Hydroxide/Magnesium Hydroxide	NCIT_C29273	[A combination preparation containing the antacids aluminum hydroxide and magnesium hydroxide. Aluminum hydroxide and magnesium hydroxide neutralize stomach acids, thereby raising the pH to reduce intestinal damage by acids.]
Active Peptic Ulcer	NCIT_C7923
Gastrointestinal Hemorrhage	NCIT_C48592	[Bleeding originating from any part of the gastrointestinal tract.]
Right Lung, Inferior Lobe, Lateral Basal Segment	NCIT_C132403	[The lateral basal segment of the inferior lobe of the right lung.]
N,N-Dimethylacetamide	NCIT_C29274
Right Lung, Inferior Lobe, Medial Basal Segment	NCIT_C132404	[The medial basal segment of the inferior lobe of the right lung.]
Right Lung, Inferior Lobe, Posterior Basal Segment	NCIT_C132405	[The posterior basal segment of the inferior lobe of the right lung.]
Urachal Epithelium	NCIT_C54210
NA17 Peptide (Amino acid sequence VLPDVFIRCV)	NCIT_C29276	[A synthetic peptide vaccine derived from the melanoma antigen NA17. Dendritic cells (DC) harvested from a cancer patient may be exposed to or pulsed with the NA17 peptide (VLPDVFIRCV). Autologous vaccination with these altered dendritic cells may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for NA17, resulting in decreased tumor growth. (NCI04)]
Right Lung, Inferior Lobe, Superior Segment	NCIT_C132406	[The superior segment of the inferior lobe of the right lung.]
Nevirapine	NCIT_C29277	[A benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS.]
Right Lung, Middle Lobe, Lateral Segment	NCIT_C132407	[The lateral segment of the middle lobe of the right lung.]
Nitroestron Meth ETH	NCIT_C29278
Efalizumab	NCIT_C68831	[A humanized IgG1 monoclonal antibody directed against CD11a, the alpha subunit of human leukocyte-function-associated antigen type 1 (LFA-1), with immunosuppressant activity. Efalizumab binds to CD11a, which is expressed on all leukocytes, resulting in a reduction in the cell surface expression of CD11a. In addition, this agent inhibits the binding of LFA-1 to intercellular adhesion molecule-1 (ICAM-1), resulting in the inhibition of leukocyte adherence and the suppression of cell-mediated immunity. LFA-1 binding to ICAM-1 is involved in the activation of T lymphocytes, adhesion of T lymphocytes to endothelial cells, and migration of T lymphocytes to sites of inflammation.]