Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Morgan County, CO	NCIT_C107976
Lymphangitis	NCIT_C34790	[Inflammation of the lymphatic vessels.]
Hypopharyngeal Cancer pT4a TNM Finding v8	NCIT_C132933	[Hypopharyngeal cancer with moderately advanced local disease. Tumor invades thyroid/cricoid cartilage, hyoid bone, thyroid gland, or central compartment soft tissue. Central compartment soft tissue includes prelaryngeal strap muscles and subcutaneous fat. (from AJCC 8th Ed.)]
Otero County, CO	NCIT_C107977
Lymphocytosis	NCIT_C34791	[A laboratory test result indicating an abnormal increase in the number of lymphocytes in the peripheral blood, effusions, or bone marrow.]
Hypopharyngeal Cancer pT4b TNM Finding v8	NCIT_C132934	[Hypopharyngeal cancer with very advanced local disease. Tumor invades prevertebral fascia, encases carotid artery, or involves mediastinal structures. (from AJCC 8th Ed.)]
Ouray County, CO	NCIT_C107978
Hemophagocytic Lymphohistiocytosis	NCIT_C34792	[A rare but potentially life-threatening disorder characterized by the proliferation of histiocytes and macrophages and phagocytosis of red blood cells, white blood cells, and platelets. It may be inherited or secondary, due to infections, autoimmune disorders, or underlying malignancies. Signs and symptoms include fever, lymphadenopathy, hepatomegaly, splenomegaly, and pancytopenia.]
Oropharyngeal (p16-Negative) Cancer Clinical Regional Lymph Nodes TNM Finding v8	NCIT_C132935	[A clinical finding about one or more characteristics of oropharyngeal (p16-negative) cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.]
Oropharyngeal (p16-Negative) Cancer Clinical TNM Finding v8	NCIT_C132911	[A clinical finding about one or more characteristics of p16-negative oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system.]
Park County, CO	NCIT_C107979
Caspase-2	NCIT_C20145	[Caspase-2 (452 aa, ~51 kDa) is encoded by the human CASP2 gene. This protein is involved in cell cycle arrest, apoptosis and proteolysis.]
Caspase	NCIT_C18153	[Caspases are a family of intracellular cysteine proteinases involved in inflammation and apoptosis. These enzymes appear to be involved in the initial signaling events, as well as the downstream proteolytic cleavages, that result in apoptotic cell death. They are specific for aspartic acid at the P1 position and are divided into two classes based on the lengths of their N-terminal pro-domains. Caspases-1, -2, -4, -5, -8, and -10 have long pro-domains; caspases-3, -6, -7, and -9 have short pro-domains. (from Science 1998. 281:1312 and Br Med Bull 1997. 53:478)]
Mitotic Recombination	NCIT_C20146	[Any type of recombination occurring within somatic cells and involving possible exchange and frequent loss of segments of DNA by either homologous or nonhomologous recombination of broken DNA strands. This process may be involved in lengthening telomeres and in resolving breaks induced by radiation, mutagenic chemicals and collapsed replication forks. Disruptions in mitotic recombination may result in predisposition to cancers.]
Metaphase Process	NCIT_C16846	[The second phase of mitosis, in which the chromosomes line up across the equatorial plane of the spindle prior to separation.]
Mitotic Chromosome	NCIT_C13430	[Condensed chromosomes observed during the M phase of the cell cycle. Individual chromosomes can be discerned and differentiated morphologically.]
DNA Maintenance	NCIT_C18300	[DNA Maintenance involves cellular mechanisms that maintain DNA integrity. In many organisms, maintenance of DNA integrity requires not only faithful DNA replication, but also DNA repair and recombination. (NCI)]
Telomere	NCIT_C13295	[A stretch of repetitive nucleotide sequences (TTAGGG repeats in humans) found at both ends of each chromatid arm that plays a role in chromosome stability during replication.]
RNA Interference	NCIT_C20153	[Sequence-specific posttranscriptional gene silencing. It is mediated by 21- and 22-nucleotide small interfering RNAs (siRNAs) generated by ribonuclease III cleavage from longer dsRNAs.]
ACF complex	NCIT_C20154	[The Drosophila gene Acf1 encodes ATP-dependent chromatin assembly factor large subunit, a component of the chromatin assembly complex involved in chromatin assembly/disassembly. Acf1 contains a PHD-finger and is able to modulate the internucleosomal spacing of chromatin by an ATP-dependent mechanism. Similar sequences have been identified in Caenorhabditis elegans, Homo sapiens, Mus musculus, and Saccharomyces cerevisiae. (from FlyBase 0027620 and NCI)]