Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Soluble Guanylate Cyclase | NCIT_C20141 | [Human Soluble Guanylate Cyclases (Adenylyl Cyclase 4/Guanylyl Cyclase Family) are heterodimeric (alpha/beta) nitric oxide-activated cytoplasmic enzymes that catalyze conversion of GTP to cGMP second messenger. The main receptors for nitric oxide in the cardiovascular system and for nitrovasodilator drugs, alpha/beta interaction is required for guanylyl cyclase activity. (NCI)] |
| Guanylate Cyclase | NCIT_C16653 | [Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are receptors for hormones, and intracellular soluble GCs that are activated by the gaseous second messenger nitric oxide (NO). EC 4.6.1.2] |
| Golgi Targeting | NCIT_C20142 | [1) To direct or use toward the Golgi apparatus as a target. Targeting of the Golgi apparatus by specific substances to disrupt or alter its function. 2) Related to structural elements in a protein, such as a peptide sequence, that directs the localization of a protein or protein complex to the Golgi apparatus.] |
| Nuclear Division | NCIT_C20143 | [A cell division process consisting of a complex series of events or phases (prophase, prometaphase, metaphase, anaphase, telophase) by means of which two daughter nuclei normally receive identical complements of the chromosomes and DNA content characteristic of the original somatic cells of the species. Part of the process by which the body grows and replaces cells. Although used interchangeably with cell division, strictly speaking the term mitosis refers to nuclear division; cytokinesis refers to division of the cytoplasm. In some cells, as in many fungi and the fertilized eggs of many insects, nuclear division occurs within the cell unaccompanied by division of the cytoplasm and formation of daughter cells.] |
| M Phase Process | NCIT_C20349 | [The last cell cycle stage during which the replicated daughter chromosomes separate in to separate nuclei; cytokinesis then occurs to produce separate daughter cells. It is divided into Prophase, Metaphase, Anaphase, and Telophase.] |
| DNA Replication Factor Cdt1 | NCIT_C20144 | [DNA replication factor Cdt1 (546 aa, ~60 kDa) is encoded by the human CDT1 gene. This protein plays a role in protein-protein interactions that are necessary for DNA replication.] |
| Licensing Factor | NCIT_C20319 | [S-phase onset is controlled, so that it occurs only once every cell cycle. DNA is licensed for replication after mitosis in G(1), and passage through S-phase removes the license to replicate. Licensing factors are required for licensing and central to ensuring that replication occurs once per cell cycle. (from J Biol Chem 2001 Nov 30;276(48):44905-11)] |
| Hypertrophic Lichen Planus | NCIT_C34779 | [A form of lichen planus that is characterized by plaques of markedly thickened skin that is often extremely pruritic and localized to the lower legs. It can result in permanent pigmentation and scarring.] |
| Hypopharyngeal Cancer cN3b TNM Finding v8 | NCIT_C132958 | [Hypopharyngeal cancer with metastasis in any node(s) and clinically overt ENE(+). (from AJCC 8th Ed.)] |
| Oropharyngeal (p16-Negative) Cancer pNX TNM Finding v8 | NCIT_C132959 | [Oropharyngeal (p16-negative) cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)] |
| Leukorrhea | NCIT_C34775 | [Whitish or yellowish mucosal vaginal discharge.] |
| Lice | NCIT_C34776 | [A taxonomic order of wingless insects that are obligate ectoparasites of birds and mammals. Lice attach tightly to hair, fur, and feathers of the host organism and feed on blood, skin, and sebaceous secretions.] |
| Insect | NCIT_C14227 | [A taxonomic class of arthropods that includes praying mantises, dragonflies, grasshoppers, true bugs, flies, bees, wasps, ants, butterflies, moths, and beetles.] |
| Atrophic Lichen Planus | NCIT_C34777 | [A rare form of lichen planus that is characterized by well-demarcated, white-bluish papules or plaques with central atrophy.] |
| Bullous Lichen Planus | NCIT_C34778 | [A rare form of lichen planus that is characterized by the formation of vesico-bullous lesions on top of preexisting lichen planus papules or on normal skin.] |
| Syngeneic Stem Cell Transplantation | NCIT_C93196 | |
| Intraluminal Intubation and Dilation | NCIT_C93197 | |
| Intubation Procedure | NCIT_C37981 | [The insertion of a cannula or tube into a hollow body organ.] |
| Transurethral Prostate Biopsy | NCIT_C93198 | [Biopsy of the prostate obtained by a needle inserted through the urethral wall.] |
| Biopsy of Prostate | NCIT_C51701 | [Removal of tissue from the prostate for microscopic examination.] |