Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
DNA Replication Initiation Protein	NCIT_C95243	[A protein that is involved in the initiation of the DNA replication process.]
Licensing Factor Gene	NCIT_C20372	[Licensing Factor Genes encode Licensing Factors that are required, after a prior round of mitosis, in G(1) for DNA replication licensing, are removed after passage through S-phase, and are central to ensuring that replication occurs once per cell cycle. (NCI)]
Replication Licensing	NCIT_C20365	[A process that limits duplication of the genome to once per cell division cycle. In eukaryotes replication origins are limited to a single initiation event during G1 by temporally separating the assembly of the pre-replication complex (pre-RC) from the initiation of DNA synthesis. An elaborate mechanism regulates the ordered loading of proteins at replication origins which convert a poised, but inactive, minichromosome maintenance (MCM) complex into an enzymatically active helicase.]
Protein Truncation	NCIT_C20314	[Termination of the translation process at a stop codon.]
Werner Syndrome ATP-Dependent Helicase	NCIT_C20316	[Werner syndrome ATP-dependent helicase (1432 aa, ~162 kDa) is encoded by the human WRN gene. This protein plays a role in both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang.]
Consumer Advocates in Research and Related Activities	NCIT_C20317	[A program to increase cancer advocate involvement in NCI's activities. It convenes a large network of dedicated advocates to give insight and feedback from the consumer's perspective to developing programs. (NCI press release)]
NCI Advisory Board or Group	NCIT_C19137
Fasiglifam	NCIT_C132780
WA09	NCIT_C20310	[Provider: Wisconsin Alumni Research Foundation (WARF), Madison, WI. Information from provider and not independently verified by NIH: Cells are positive for cell markers SSEA-3, SSEA-4, TRA-1-60, TRA-1-81, and alkaline phosphatase; Cells are negative for SSEA-1; Give rise to teratomas containing derivatives of three germ layers in SCID mice; Differentiate in vitro; Cells not yet ready for distribution. Publications: Thomson et al., Science 282, 1145, 1998; Amit et al., Developmental Biology 227, 271, 2000. This cell line meets the criteria for the use of human embryonic stem cells by federally funded researchers.]
Stage I Major Salivary Gland Cancer AJCC v8	NCIT_C132781	[Stage I includes: T1, N0, M0. T1: Tumor measuring 2 cm or less in greatest dimension without extraparenchymal extension. Extraparenchymal extension is clinical or macroscopic evidence of invasion of soft tissues. Microscopic evidence alone does not constitute extraparenchymal extension for classification purposes. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)]
WA13	NCIT_C20311	[Provider: Wisconsin Alumni Research Foundation (WARF), Madison, WI. Information from provider and not independently verified by NIH: Cells are positive for cell markers SSEA-3, SSEA-4, TRA-1-60, TRA-1-81, and alkaline phosphatase; Cells are negative for SSEA-1; Give rise to teratomas containing derivatives of three germ layers in SCID mice; Differentiate in vitro; Cells not yet ready for distribution. Publication: Thomson et al., Science 282, 1145, 1998. This cell line meets the criteria for the use of human embryonic stem cells by federally funded researchers.]
European Union Drug Regulating Authorities Clinical Trials Database	NCIT_C132782	[The European Union's electronic database of clinical trials. It contains information submitted by sponsors and informs users about ongoing clinical trials in EU Member States and European Economic Area countries.]
WA14	NCIT_C20312	[Provider: Wisconsin Alumni Research Foundation (WARF), Madison, WI. Information from provider and not independently verified by NIH: Cells are positive for cell markers SSEA-3, SSEA-4, TRA-1-60, TRA-1-81, and alkaline phosphatase; Cells are negative for SSEA-1. Give rise to teratomas containing derivatives of three germ layers in SCID mice; Differentiate in vitro; Cells not yet ready for distribution. Publication: Thomson et al., Science 282, 1145, 1998. This cell line meets the criteria for the use of human embryonic stem cells by federally funded researchers.]
Stage 0 Major Salivary Gland Cancer AJCC v8	NCIT_C132783	[Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)]
University Medical Information Network	NCIT_C132784	[A cooperative organization for national medical schools in Japan designed to: provide up-to-date information to healthcare professionals; promote communications between healthcare professionals; support collaborative work among university hospitals; support collaborative medical research; standardize medical data and collect hospital statistics; support education and training at hospitals.]
Replication Initiation Point Mapping	NCIT_C20320	[Replication initiation point (RIP) mapping detects start sites for DNA synthesis at the nucleotide level and thus monitors replication initiation events at the origin very precisely. Beyond detecting the precise positions of start sites, the application of RIP mapping in yeast and human cells has revealed a single, defined start point at which replication initiates. (J Cell Sci 2001 Feb;114(Pt 4):643-51)]
Gene Mapping	NCIT_C16438	[Determination of the relative positions of genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them.]
Male Orgasmic Disorder	NCIT_C34959	[Persistent delay or absence in orgasm not accounted for by a medical reason.]
Sexual and Gender Identity Disorders	NCIT_C92202	[A category of psychiatric disorders characterized by a disturbance in sexual desire and in the psychophysiological changes that make up the sexual response cycle.]
Pseudogout	NCIT_C34955	[An acute episode of pain, swelling, and redness, sometimes associated with fever. It is caused by the deposition of calcium pyrophosphate crystals in the joints.]