Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Light-Scattering Spectroscopy	NCIT_C20059	[The nuclei of precancerous lesions are distinct in that they become enlarged, crowded and hyperchromatic. Light-scattering spectroscopy can diagnose early epithelial cancers based on the scattering of light through their enlarged nuclei. (from Medscape)]
Spectroscopy	NCIT_C17155	[The technique of measuring the emission and absorption of different wavelengths (spectra) of visible and non-visible light. This can be done via a spectroscope, which consists of a slit, prism, collimator lens, object lens, and a grating.]
Conformation Dependent Mutation Detection	NCIT_C20064	[Polymorphism, single-stranded conformational, detection. Altered migration of single-stranded DNA molecules in non-denaturing gels based upon 3-D conformation. Uses PCR and/or restriction enzymes to generate short dsDNA molecules spanning a sequence of interest. The dsDNA molecules are heat denatured, and then quickly cooled. Each ssDNA molecule will assume a secondary structure (conformation) dependent upon its unique sequence. Base mutations will often result in altered conformations, with altered mobilities, which can be visualized following separation in non-denaturing gels. (NCI/OSP)]
Polymorphism Analysis	NCIT_C18309	[Chemical or physical tests to determine DNA sequence variation]
Microdeposition	NCIT_C20065	[Thin layer deposition. Commonly used in integrated circuit fabrication.]
Microfabrication	NCIT_C20066	[The processing techniques, such as deposition, etching, and patterning, that are utilized to produce miniaturized structures and devices with feature sizes and resolution in the micron domain. Uses a combination of micromachining and integrated circuit fabrication technology. (from U. Louisville course description)]
Modeling of Cellular Pathways	NCIT_C20067	[Any representation of the individual steps in a metabolic pathway of a cell.]
Computer Modeling	NCIT_C16461	[A technique which attempts to provide an abstract model of a particular system. It utilizes a mathematical model, which attempts to predict the behavior of the system from a set of parameters and initial conditions.]
Cyclin-Dependent Kinase Inhibitor Gene	NCIT_C18593	[The CDK Inhibitor Genes encode the CDK Inhibitor Proteins, a group of low molecular weight proteins that associate with cyclin-CDK complexes or CDKs alone and inhibit their activity. (From OMIM and NCI)]
Multiple Endocrine Neoplasia Type 4	NCIT_C157449	[An autosomal dominant tumor syndrome caused by germline CDKN1B mutations that result in a phenotype similar to that of multiple endocrine neoplasia type 1, characterized by endocrine neoplasms, particularly in the parathyroid glands, pituitary, and pancreas. (WHO 2017)]
Neuregulin Receptor	NCIT_C20061	[Comprised of the erbB2, erbB3, and erbB4 proteins. These proteins form homo and heterodimers, which complicates the assignment of specificities: it is known that erbB2 homodimer do not bind heregulin, but erbB2/erbB3 heterodimers do.]
Cellular Compartment Analysis	NCIT_C20062	[Cell partitioning techniques used to determine the subcellular distribution of molecules of interest.]
Combinatorial Synthesis of Small Molecules	NCIT_C20063	[Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made. Combinatorial synthesis is not random, but systematic and repetitive, using sets of chemical "building blocks" to form a diverse set of molecular entities. Initial synthesis is usually made on a solid substrate. The technique lays down the materials in a checkerboard arrangement, as thin squares arranged in a grid. Scientists use combinatorial chemistry to create large populations of molecules, or libraries, that can be screened efficiently en masse. (NCI/OSP)]
Combinatorial Synthesis	NCIT_C19321	[Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made. Combinatorial synthesis is not random, but systematic and repetitive, using sets of chemical "building blocks" to form a diverse set of molecular entities. Initial synthesis is usually made on a solid substrate. The technique lays down the materials in a checkerboard arrangement, as thin squares arranged in a grid. Scientists use combinatorial chemistry to create large populations of molecules, or libraries, that can be screened efficiently en masse.]
Q-LES-Q - Felt Full of Pep and Vitality	NCIT_C130615	[Quality Of Life Enjoyment And Satisfaction Questionnaire (Q-LES-Q) With regard to your physical health, during the past week how much of the time have you: felt full of pep and vitality?]
Q-LES-Q - Free of Visual Problems	NCIT_C130616	[Quality Of Life Enjoyment And Satisfaction Questionnaire (Q-LES-Q) With regard to your physical health, during the past week how much of the time have you: been free of visual problems?]
Q-LES-Q - Felt Clearheaded	NCIT_C130617	[Quality Of Life Enjoyment And Satisfaction Questionnaire (Q-LES-Q) During the past week how much of the time have you: felt clearheaded?]
Q-LES-Q - Felt Satisfied With Your Life	NCIT_C130618	[Quality Of Life Enjoyment And Satisfaction Questionnaire (Q-LES-Q) During the past week how much of the time have you: felt satisfied with your life?]
Q-LES-Q - Felt Good About Your Appearance	NCIT_C130619	[Quality Of Life Enjoyment And Satisfaction Questionnaire (Q-LES-Q) During the past week how much of the time have you: felt good about your appearance?]
KRT5 wt Allele	NCIT_C105680	[Human KRT5 wild-type allele is located in the vicinity of 12q13.13 and is approximately 6 kb in length. This allele, which encodes keratin, type II cytoskeletal 5 protein, plays a role in the formation of the epidermis. Mutation of the gene is associated with Dowling-Degos disease and several subtypes of epidermolysis bullosa simplex.]