Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Vulvar Cancer TNM Finding v8 | NCIT_C139590 | [A finding about one or more characteristics of vulvar cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to all carcinomas of the vulva. Melanoma of the vulva is staged according to the classification for melanoma of the skin. (from AJCC 8th Ed.)] |
| Vulvar Cancer Clinical TNM Finding v8 | NCIT_C139591 | [A clinical finding about one or more characteristics of vulvar cancer, following the rules of the TNM AJCC v8 classification system.] |
| Bazedoxifene | NCIT_C73598 | [An indole derivative and third-generation selective estrogen receptor modulator (SERM) with potential antineoplastic activity. Upon administration, bazedoxifene specifically binds to estrogen receptors in responsive tissues, including liver, bone, breast, and endometrium. The resulting ligand-receptor complex is translocated to the nucleus where, depending on the tissue type, it either promotes or suppresses the transcription of estrogen-regulated genes. Bazedoxifene acts as an estrogen antagonist in uterine and breast tissue, thereby blocking the proliferative effects of estrogen-binding to ER-positive cells in these tissues. Bazedoxifene functions as an estrogen agonist in lipid metabolism, thereby decreasing total and LDL cholesterol levels. In bone, it decreases bone resorption and bone turnover and increases bone mineral density.] |
| Import | NCIT_C73599 | [An activity concerned with bringing any good, commodity, or service from a foreign source.] |
| Marketed under New Drug Application | NCIT_C73594 | [A category specifying that a product is marketed under a New Drug Application.] |
| Menadiol | NCIT_C73595 | |
| Mebeverine Hydrochloride | NCIT_C73596 | [The hydrochloride salt form of mebeverine, an orally bioavailable reserpine derivative and anticholinergic agent, with spasmolytic activity. Upon administration, mebeverine targets, binds to and blocks the muscarinic receptors on smooth muscle cells in target tissues, such as the gastrointestinal (GI) tract, uterus, gallbladder and bladder. This prevents smooth muscle contraction and relaxes smooth muscle. Additionally, this may prevent spasms, ease pain and cramps in the GI tract and improve incontinence. In addition, mebeverine stabilizes excitable membranes by decreasing the permeability of ion channels and preventing intracellular calcium accumulation. This agent also blocks noradrenaline reuptake by sympathetic nerve endings and exerts a local anesthetic effect.] |
| Oxybutynin Chloride | NCIT_C73597 | [The chloride salt form of oxybutynin, a tertiary amine and anticholinergic agent with antispasmodic activity. Oxybutynin chloride exerts its antimuscarinic effect on bladder smooth muscle by blocking muscarinic receptors in smooth muscle, thereby inhibiting acetylcholine binding. This results in a relaxation of bladder smooth muscle, a reduction of involuntary muscle contractions and delays the initial desire to void.] |
| Medical Product Marketing Category | NCIT_C73580 | |
| Medical Product Characteristics | NCIT_C53450 | [The distinguishing qualities of a medical product.] |
| SPL Marketing Category Terminology | NCIT_C73582 | [Terminology used for representation of the information on pharmaceutical product marketing category in the framework of the Structured Product Labeling documents.] |
| Pock Forming Unit | NCIT_C73576 | [A measure of viable infectious entities (e.g. viral particles or group of particles) in the specimen or product defined as the smallest quantity of a viral suspension that can produce a cytopathic effect in the host chick chorio-allantoic membrane challenged with the defined inoculum, visible under the microscope and/or to the naked eye as a pock.] |
| Pressor Unit per Milliliter | NCIT_C73577 | [The activity of a pressor agent expressed in pressor units per milliliter.] |
| Protein Nitrogen Unit per Milliliter | NCIT_C73578 | [A measurement of the strength of an allergenic extract, one protein nitrogen unit/mL (PNU/mL) is 0.01 microgram of phosphotungstic acid-precipitable protein nitrogen dissolved in one mL of antigen extract.] |
| Milliequivalent per Milligram | NCIT_C73572 | [A unit of relative amount of substance content equivalent to the content at which one milligram of mixture contains one thousandth of an equivalent of a component. The unit is also used as a dose calculation unit.] |
| Milligram Titer | NCIT_C73573 | [A unit of measurement of substance concentration in a solution as determined by the quantitative reaction with added measured volume(s) of a solution of the precisely known concentration(s) of a standard reagent expressed in milligrams.] |
| Plaque Forming Unit Equivalent 1000 Mouse LD50 | NCIT_C73575 | |
| Marketed for Export Only | NCIT_C73590 | [A category specifying that a product is marketed for export only.] |
| Sodium Dichloroacetate | NCIT_C73591 | [The sodium salt of dichloroacetic acid with potential antineoplastic activity. Dichloroacetate ion inhibits pyruvate dehydrogenase kinase, resulting in the inhibition of glycolysis and a decrease in lactate production. This agent may stimulate apoptosis in cancer cells by restoring normal mitochondrial-induced apoptotic signaling.] |
| Lysine Hydrochloride | NCIT_C73592 |