Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Interpretation	NCIT_C41255	[An act or process of elucidation, explication, or explanation of the meaning of an event or thing.]
APC8015F	NCIT_C48640	[A cell-based vaccine composed of previously frozen autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP.]
Dendritic Cell Tumor Peptide Vaccine	NCIT_C1987	[A vaccine composed of dendritic cells pulsed with peptide epitopes that stimulate cytotoxic T lymphocyte anti-tumor activity. (NCI)]
Once Daily	NCIT_C125004	[Scheduled or occurring at a frequency of once per day.]
Reversal	NCIT_C125005	[A change in something from one state to the opposite state.]
Pathologic Examination	NCIT_C125006	[An assessment of disease process to include cause, development, and/or structural and functional changes associated with the disease.]
Histopathology Result	NCIT_C125007	[The outcome of a microscopic pathologic examination using various cytochemical and immunocytochemical stains.]
Ginseng Compound	NCIT_C125000	[A compound containing the traditional Chinese medicine (TCM) ginseng, a herb belonging to the Araliaceae family, with potential antioxidant, chemopreventive, anti-inflammatory and antineoplastic activities. Upon administration of the ginseng compound, the active ingredients, mainly ginsenosides, inhibit various signal transduction pathways that play key roles in carcinogenesis and inflammation. This leads to the induction of apoptosis in and inhibits proliferation of tumor cells. In addition, ginsenosides enhance the activity of various antioxidant enzymes, induce nitric oxide (NO) formation, inhibit the formation of reactive oxygen species (ROS) and protect against free radical-induced DNA damage. Ginseng also modulates various components of the immune system, including the activation of dendritic cells (DCs).]
Huaier Extract Granule	NCIT_C125001	[An orally bioavailable traditional Chinese medicine (TCM) composed of a granule containing an aqueous extract of Trametes robiniophila murr (Huaier), a mushroom found on hardwood tree trunks, with potential antineoplastic and anti-angiogenic activities. Although the exact mechanism of action through which Huaier exerts its effects is largely unknown, upon administration, this agent induces cell cycle arrest and apoptosis, and inhibits proliferation and migration of susceptible cancer cells through the modulation of various signal transduction pathways involved in carcinogenesis and angiogenesis.]
Topical Trichloroacetic Acid	NCIT_C125002	[A topical solution containing the caustic agent trichloroacetic acid (TCA), with potential keratolytic, anti-viral and antineoplastic activities. Upon topical application to the affected area, TCA causes tissue necrosis through coagulation of proteins, leads to the destruction of human papilloma virus (HPV)-associated warts and inhibits HPV-driven proliferation of cancer cells.]
pan-RAF Inhibitor LXH254	NCIT_C125003	[An orally available inhibitor of all members of the serine/threonine protein kinase Raf family, with potential antineoplastic activity. Upon administration, pan-RAF inhibitor LXH254 binds to Raf proteins and inhibits Raf-mediated signal transduction pathways. This inhibits proliferation of Raf-overexpressing tumor cells. Raf protein kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are upregulated in a variety of cancer cell types. They play key roles in tumor cell proliferation and survival.]
Neuronal Cell Adhesion Molecule	NCIT_C34001	[Neuronal cell adhesion molecule (1304 aa, ~144 kDa) is encoded by the human NRCAM gene. This protein plays a role in both neuronal development and neuron-neuron adhesion.]
Neurotrophin-3	NCIT_C34002	[Neurotrophin-3 (257 aa, ~29 kDa) is encoded by the human NTF3 gene. This protein plays a role in the survival of sensory neurons.]
Hypochondriac Region	NCIT_C34003	[The superior portion of the abdomen that lies inferior to the right and left costal margins and lateral to the epigastrum on both the right and left sides of the body.]
Quantitation Range	NCIT_C125010	[A set of values that demarcate the detection limits for a specific assay.]
Test Result Report	NCIT_C70950	[An account of the outcome of an analysis or test.]
Nuclear Receptor Subfamily 0 Group B Member 2	NCIT_C34000	[Nuclear receptor subfamily 0 group B member 2 (257 aa, ~28 kDa) is encoded by the human NR0B2 gene. This protein plays a role in the negative regulation of transcription.]
Sexual Precocity	NCIT_C48628	[Unusually early sexual development or maturity; premature puberty.]
Vaginal Cancer pN1 TNM Finding v8	NCIT_C139656	[Vaginal cancer with pelvic or inguinal lymph node metastasis. (from AJCC 8th Ed.)]
Vaginal Cancer Pathologic Regional Lymph Nodes TNM Finding v8	NCIT_C139652	[A pathologic finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.]