Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Radial Artery of the Endometrium | NCIT_C34013 | [Arteries that arises from the arcuate arteries in the myometrium and supply small straight arteries to the basal layer of the endometrium and spiral arteries to the functional zone of the endometrium.] |
| Endometrium | NCIT_C12313 | [The mucous membrane comprising the inner layer of the uterine wall; it consists of a simple columnar epithelium and a lamina propria that contains simple tubular uterine glands. The structure, thickness, and state of the endometrium undergo marked change with the menstrual cycle.] |
| Origin Recognition Complex Subunit 2 | NCIT_C34014 | [Origin recognition complex subunit 2 (577 aa, ~66 kDa) is encoded by the human ORC2 gene. This protein is involved in DNA replication initiation.] |
| Origin Recognition Complex Subunit 3 | NCIT_C34015 | [Origin recognition complex subunit 3 (711 aa, ~82 kDa) is encoded by the human ORC3 gene. This protein plays a role in the promotion of DNA replication.] |
| Stage IV Vulvar Cancer AJCC v8 | NCIT_C139627 | [Stage IV includes: T1-T3, N3, M0-M1. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). T3: Tumor of any size with extension to any of the following: upper/proximal two-thirds of the urethra, upper/proximal two-thirds of the vagina, bladder mucosa, or rectal mucosa; or fixed to pelvic bone. N3: Fixed or ulcerated regional lymph node metastasis. M0: No distant metastasis. M1: Distant metastasis (including pelvic lymph node metastasis). (from AJCC 8th Ed.)] |
| Stage IVA Vulvar Cancer AJCC v8 | NCIT_C139628 | [Stage IVA includes: (T1-T2, N3, M0); (T3, Any N, M0). T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). T3: Tumor of any size with extension to any of the following: upper/proximal two-thirds of the urethra, upper/proximal two-thirds of the vagina, bladder mucosa, or rectal mucosa; or fixed to pelvic bone. N3: Fixed or ulcerated regional lymph node metastasis. M0: No distant metastasis. (from AJCC 8th Ed.)] |
| Olfactory Receptor 1G1 | NCIT_C34010 | [Olfactory receptor 1G1 (313 aa, ~35 kDa) is encoded by the human OR1G1 gene. This protein is involved in odorant binding and ligand-dependent signal transduction.] |
| Origin Recognition Complex Subunit 1 | NCIT_C34011 | [Origin recognition complex subunit 1 (861 aa, ~97 kDa) is encoded by the human ORC1 gene. This protein plays a role in DNA replication.] |
| Stage III Vulvar Cancer AJCC v8 | NCIT_C139623 | [Stage III includes: T1-T2, N1-N2c, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N1: Regional lymph node metastasis with one or two lymph node metastases each less than 5 mm, or one lymph node metastasis equal to 5 mm. N2a: Three or more lymph node metastases each less than 5 mm. It includes micrometastasis, N2mi. N2b: Two or more lymph node metastases equal to 5 mm. N2c: Lymph node(s) metastasis with extranodal extension. M0: No distant metastasis. (AJCC 8th Ed.)] |
| Stage IIIA Vulvar Cancer AJCC v8 | NCIT_C139624 | [Stage IIIA includes: T1-T2, N1, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N1: Regional lymph node metastasis with one or two lymph node metastases each less than 5 mm, or one lymph node metastasis equal to 5 mm. M0: No distant metastasis. (AJCC 8th Ed.)] |
| Stage IIIB Vulvar Cancer AJCC v8 | NCIT_C139625 | [Stage IIIB includes: T1-T2, N2a, N2b, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N2a: Three or more lymph node metastases each less than 5 mm. It includes micrometastasis, N2mi. N2b: Two or more lymph node metastases equal to 5 mm. M0: No distant metastasis. (AJCC 8th Ed.)] |
| Stage IIIC Vulvar Cancer AJCC v8 | NCIT_C139626 | [Stage IIIC includes: T1-T2, N2c, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N2c: Lymph node(s) metastasis with extranodal extension. M0: No distant metastasis. (AJCC 8th Ed.)] |
| Cannot Be Assessed | NCIT_C48657 | [Aspects of the context prevent the evaluation needed to determine a value.] |
| Indeterminate | NCIT_C48658 | [Cannot distinguish between two or more possible values in the current context.] |
| Stage IA Vulvar Cancer AJCC v8 | NCIT_C139620 | [Stage IA includes: T1a, N0, M0. T1a: Lesion measuring 2 cm or less, confined to the vulva and/or perineum, and with stromal invasion of 1.0 mm or less. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)] |
| Stage IB Vulvar Cancer AJCC v8 | NCIT_C139621 | [Stage IB includes: T1b, N0, M0. T1b: Lesion measuring more than 2 cm, or any size with stromal invasion of more than 1.0 mm, confined to the vulva and/or perineum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)] |
| Stage II Vulvar Cancer AJCC v8 | NCIT_C139622 | [Stage II includes: T2, N0, M0. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)] |
| Gene Identifier | NCIT_C48664 | [A unique gene name within a specific repository, database, or collection.] |
| Elapse | NCIT_C48665 | [To pass by; having passed by.] |
| Low Penetrance Allele | NCIT_C48666 | [A gene with a low probability of expression as a phenotype.] |