Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Parecoxib Sodium	NCIT_C73831	[A water-soluble, injectable sodium salt form of parecoxib, an amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, with anti-inflammatory, analgesic, and antipyretic activities. Upon intravenous or intramuscular administration, parecoxib is hydrolyzed by hepatic carboxyesterases to its active form, valdecoxib. Valdecoxib selectively binds to and inhibits COX-2. This prevents the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and, therefore, does not interfere with blood coagulation.]
Remoxipride Hydrochloride	NCIT_C73832
Recurrent Cancer TNM Finding	NCIT_C48880	[TNM staging performed for recurrent cancer.]
Clinical TNM Finding	NCIT_C48881	[TNM staging performed with access to clinical information only.]
Autopsy TNM Finding	NCIT_C48882	[TNM staging performed on autopsy.]
Neurula	NCIT_C34229	[An stage in embryonic development during which neurulation takes place, and which follows the gastrula stage.]
Sodium Bisulfite	NCIT_C73837
Sitagliptin	NCIT_C73838	[An orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis.]
Dipeptidyl Peptidase-4 Inhibitor	NCIT_C98086	[Any inhibitor of the proline-specific serine protease dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. DPP-4 inhibitors bind to DPP-4 and inhibit the breakdown of the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This prolongs incretin activity, increases postprandial insulin release, decreases glucagon release, delays gastric emptying and lowers blood glucose levels. The risk for hypoglycemia is negligible with the use of DPP-4 inhibitors.]
Revaprazan Hydrochloride	NCIT_C73839	[The hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Revaprazan concentrates highly in the gastric parietal cell canaliculus and on entering this acidic environment is instantly protonated and binds competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.]
Neural Plate	NCIT_C34225	[A thickened area of ectoderm on the posterior aspect of the trilaminar embryo that will give rise to the nervous system.]
Prinomide	NCIT_C73833
Pivampicillin Hydrochloride	NCIT_C73834	[The hydrochloride salt form of a semisynthetic, orally active pivalate ester of ampicillin with antibacterial activity. Upon absorption, pivampicillin is hydrolyzed into its active form ampicillin by esterases. Ampicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.]
Penicillin Antibiotic	NCIT_C1500	[Any beta-lactam antibiotic derived from Pencillium fungi with bactericidal activity. Penicillin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.]
Neurenteric Canal	NCIT_C34227	[A small, temporary passage between the amniotic cavity and yolk sac arising from the proximal part of the notochordal canal in the early embryo, which obliterates at the completion of the notochord.]
Pivampicillin Pamoate	NCIT_C73835	[The pamoate salt form of a semisynthetic, orally active pivalate ester of ampicillin with antibacterial activity. Upon absorption, pivampicillin is hydrolyzed into its active form ampicillin by esterases. Ampicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.]
Neuroepithelial Tissue	NCIT_C41409	[Tissue composed of neuroepithelial cells. The latter include astrocytes, oligodendrocytes, ependymal cells, neuroblasts, and olfactory receptor cells.]
Symetine Hydrochloride	NCIT_C73836
Parachordal Cartilage	NCIT_C34243	[The basal plate that forms around the cranial end of the notochord during early embryonic development, and which will eventually fuse across the midline to form the base of the occipital bone.]
Pectinate Line	NCIT_C34245	[An anatomical line of demarcation that separates the upper and lower part of the anal canal, both in structure and neurovascular supply, reflecting the different embryologic origin; superior to the line the epithelium is a mucous membrane like the rest of the gastrointestinal tract and inferiorly the epithelium is considered cutaneous, and is composed of stratified squamous keratinized with hair and sebaceous glands.]