Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Pharyngeal Apparatus	NCIT_C34248	[The collection of pharyngeal arches, pouches, clefts, and membranes present during early embryonic development that contribute to the formation of the face and neck.]
Pharyngeal Membrane	NCIT_C34251	[A double-layered, thin, membranous sheet, composed of ectoderm and endoderm, that separates the pharyngeal pouch from the pharyngeal groove in the developing embryo.]
HIV Lipodystrophy	NCIT_C48899	[A neoplastic process characterized by a diffuse poorly circumscribed overgrowth of adipose tissue in the breast and cervical areas, and an accumulation of visceral fat. It is associated with antiretroviral therapy. Clinical presentation includes hyperlipidemia, insulin resistance, and fat atrophy of the face and limbs.]
Lipomatosis	NCIT_C3193	[A neoplastic process characterized by diffuse overgrowth of mature adipose tissue.]
Talopram Hydrochloride	NCIT_C73810
Cevipabulin Fumarate	NCIT_C73815	[The fumarate salt of cevipabulin, a synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth., a small, water soluble, synthetic tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and may reduce cellular growth.]
Pibrozelesin Hydrobromide	NCIT_C73816	[The hydrobromide salt form of pibrozelesin, a semisynthetic water-soluble derivative of the antineoplastic antibiotic duocarmycin B2, with antineoplastic activity. Activated by carboxyl esterase, pibrozelesin alkylates DNA by binding to adenine-thymine (A-T)-rich sequences in the minor groove of DNA, thereby inhibiting DNA replication and inducing apoptosis.]
Duocarmycin Antineoplastic Antibiotic	NCIT_C2156	[A spirocyclopropylhexadienone-containing antineoplastic antibiotic isolated from Streptomyces bacterial species or derived synthetically. Duocarmycin antibiotics alkylate DNA by binding to adenine-thymine (A-T)- rich sequences in the minor groove of DNA, thereby inhibiting DNA replication and inducing apoptosis.]
Spirotriazine Hydrochloride	NCIT_C73817
Pyritidium Bromide	NCIT_C73818
Periderm	NCIT_C34247	[The outermost and transient layer of the epidermis of the early embryo and fetus, existing into approximately the six month of gestation, that is composed of simple squamous epithelium.]
Sitagliptin Phosphate	NCIT_C73811	[The phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis.]
Prizidilol Hydrochloride	NCIT_C73812
Quinazosin Hydrochloride	NCIT_C73813
Cetaben	NCIT_C73814	[A unique, PPARalpha-independent peroxisome proliferator with hypolipidemic activity. Cetaben decreases serum cholesterol levels by inhibiting cholesterol biosynthesis.]
Primitive Groove	NCIT_C34265	[A narrow, longitudinal, midline fissure on the surface of the primitive streak, ending at the primitive pit, that results from the active involution of cells forming the primitive streak.]
Primitive Streak	NCIT_C28402	[A thickened, linear band on the dorsal aspect of the embryonic disc, which elongates by the addition of cells to its caudal end, establishing bilateral symmetry and representing the site of cell migration during gastrulation.]
Primitive Node	NCIT_C34266	[The small circular, localized expansion of the cranial end of the primitive streak, which is centered around the primitive pit, and is where gastrulation takes place.]
Primitive Pit	NCIT_C34267	[A small depression in the center of the primitive node, located at the cranial end of the primitive groove, and the site of cranial epiblast extension, forming the initial axial process.]
Primordial Gut	NCIT_C34268	[Intraembryonic endoderm from the head, tail, and lateral folds of the early embryo that incorporate the dorsal part of the yolk sac, forming a tube-like structure extending from the buccopharyngeal membrane to the cloacal membrane, which will eventually differentiate into the digestive tract.]