Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Chemical Pneumonitis	NCIT_C35316	[Inflammation of the lungs caused by the inhalation or aspiration of chemicals.]
Lamellar Body Mimetic Mouth Spray LMS-611	NCIT_C126333	[A suspension-based oral spray containing multilamellar lipid vesicles in which the lipids mimic the lipidic composition of endogenous extra-alveolar lamellar bodies, with muco-restorative and protective activity against radiotherapy (RT)-induced xerostomia (RIX). Upon sublingual administration of the lamellar body mimetic LMS-611 using a spray, the lipids in this agent mimic the natural secretions of endogenous lamellar bodies. This makes mucus more fluid and may prevent dryness of the mouth. This restores saliva functions and makes it easier to chew, swallow and talk, and also prevents xerostomia-induced infections, tooth decay and tooth enamel decay. RT decreases saliva secretion by causing the destruction of the parotid and submandibular serous salivary glands and lamellar bodies. This results in thicker and more visco-adhesive saliva, which causes various xerostomia-induced symptoms; intact lamellar bodies maintain the fluidity of mucus and lubricate the mouth.]
Radioprotective Agent	NCIT_C797	[A pharmacological agent that protects the recipient from the damage that may result from exposure to ionizing radiation.]
Percent Activity	NCIT_C74925	[The rate of measured activity divided by the rate of total activity of a given object. It is expressed as a percentage.]
Anti-FGFR4 Monoclonal Antibody U3-1784	NCIT_C126334	[A human monoclonal antibody against human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, U3-1784 specifically binds to and blocks FGFR4. This prevents the activation of FGFR4, inhibits FGFR4-mediated signaling and leads to an inhibition of cell proliferation in FGFR4-overexpressing tumor cells. FGFR4, a receptor tyrosine kinase overexpressed by certain tumor cell types, is involved in tumor cell proliferation, differentiation, angiogenesis, and survival.]
Anti-FGFR Monoclonal Antibody	NCIT_C133879	[Any monoclonal antibody directed against te antigen fibroblast growth factor receptor (FGFR).]
Cholecystitis with Cholelithiasis	NCIT_C35332	[An acute or chronic inflammation of the gallbladder associated with the presence of gallstones.]
Cystic Duct Stone	NCIT_C35333	[A concretion in the cystic duct.]
Gallbladder Stone	NCIT_C34443	[Single or multiple, ovoid or irregular, solid particles that are formed from bile, cholesterol, and calcium in the gallbladder cavity.]
Acute Cholangitis	NCIT_C35334	[Cholangitis that is both sudden in onset and of a relatively short duration.]
Cholangitis	NCIT_C26718	[An acute or chronic inflammatory process affecting the biliary tract.]
Activating PI3K Gene Mutation	NCIT_C126340	[A change in the nucleotide sequence of any one of the genes encoding proteins in the phosphatidylinositol 3-kinase (PI3K) family that results in constitutive PI3K activity and aberrant activation of PI3K-dependent signaling pathways.]
PI3K Gene Mutation	NCIT_C157554	[A change in the nucleotide sequence in a PI3K family gene.]
Chronic Cholangitis	NCIT_C35335	[Cholangitis that is persistent and long-standing.]
CTLA4 Haploinsufficiency	NCIT_C126341	[A somatic mutation in the CTLA4 gene resulting in only a single functional gene. Haploinsufficiency for CTLA4 is associated with autoimmune lymphoproliferative syndrome, type V.]
Autoimmune Disease	NCIT_C2889	[A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis).]
Eosinophilic Gastroenteritis	NCIT_C35330	[Gastroenteritis that is characterized by eosinophilic infiltration.]
Gastroenteritis	NCIT_C34632	[An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting.]
Acute Hepatitis	NCIT_C35331	[Acute inflammation of the liver.]
Flange Device	NCIT_C49959	[A protruding edge designed to strengthen or stabilize a device or facilitate its attachment to a surface.]