Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Rat Ameloblastic Odontoma	NCIT_C60326
Rat Odontoma	NCIT_C60483
Rat Ameloblastoma	NCIT_C60327
Rat Benign Odontogenic Tumor	NCIT_C60353
Rat Angiomatous Hyperplasia	NCIT_C60328
d-Alpha-Tocopherol Acetate	NCIT_C74962
Vitamin E Acetate	NCIT_C2834	[The acetate ester of a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acid), vitamin E is a generic name for a group of compounds known as tocopherols and tocotrienols (tocols). This agent is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04)]
d-Alpha-Tocopherol Succinate	NCIT_C74963
ALX4 Gene	NCIT_C74965	[This gene is involved in both skull and limb development and transcriptional regulation.]
Homeobox Gene	NCIT_C16615	[A family of genes that contain a highly conserved sequence of approximately 180 nucleotides, which encode an approximately 60 amino acid helix-turn-helix DNA binding domain made up of 2 antiparallel alpha helices and one nearly perpendicular alpha helix connected by short chains of unstructured amino acid sequences. This gene family is involved in transcriptional regulation during embryonic development.]
Limb Development	NCIT_C19946	[Interdependent positional signaling by the apical ectodermal ridge, the posterior mesenchyme zone of polarizing activity, and the non ridge ectoderm coordinate limb bud outgrowth and patterning, Limb Development, by migrated lateral plate mesoderm and somite cells. Proximal-distal differentiating mesenchymal cells condense to form the limb skeletal primordia.]
Alpha-Tocopherol	NCIT_C74960	[The orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.]
Tocopherol	NCIT_C68313	[A class of vitamin E compounds naturally found in many different sources, such as oils, nuts, and vegetables. Tocopherols have antioxidant activity.]
dl-Alpha-Tocopherol Acetate	NCIT_C74961
ALX4 wt Allele	NCIT_C74966	[Human ALX4 wild-type allele is located in the vicinity of 11p11.2 and is approximately 50 kb in length. This allele, which encodes homeobox protein aristaless-like 4, plays a role in transcriptional regulation. Mutation of the gene is associated with parietal foramina 2.]
11p11.2	NCIT_C13570	[A chromosome band present on 11p]
Open Fracture of Neck of Metacarpal Bone	NCIT_C35358	[A traumatic break in the area of the metacarpal bone located between the diaphysis and the distal metaphysis that involves a break in the adjacent skin.]
Homeobox Protein Aristaless-Like 4	NCIT_C74967	[Homeobox protein aristaless-like 4 (411 aa, ~44 kDa) is encoded by the human ALX4 gene. This protein is involved in the regulation of transcription during skull and limb development.]
Burn of Axilla	NCIT_C35359	[A traumatic injury to the axilla resulting from exposure to caustic chemicals, extreme heat, extreme cold, or excessive radiation.]
Burn	NCIT_C34441	[A traumatic injury involving interruption of tissue cohesiveness that results from exposure to caustic chemicals, extreme heat, extreme cold or excessive radiation.]