Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| PPP1CA Gene | NCIT_C24690 | [This gene plays a role in the regulation of mitosis and glycogen metabolism.] |
| HRK wt Allele | NCIT_C49422 | [Human HRK wild-type allele is located in the vicinity of 12q24.23 and is less than 1 kb in length. This allele, which encodes activator of apoptosis harakiri protein, is involved in the regulation of apoptosis.] |
| HRK Gene | NCIT_C20418 | [This gene plays a role in apoptotic activation.] |
| Twenty Three | NCIT_C126885 | [A natural number greater than twenty-two and less than twenty-four and the quantity that it denotes.] |
| Twenty Six | NCIT_C126886 | [A natural number greater than twenty-five and less than twenty-seven and the quantity that it denotes.] |
| Twenty Seven | NCIT_C126887 | [A natural number greater than twenty-six and less than twenty-eight and the quantity that it denotes.] |
| Twenty Eight | NCIT_C126888 | [A natural number greater than twenty-seven and less than twenty-nine and the quantity that it denotes.] |
| Inattention/Hyperactivity Composite Score | NCIT_C126881 | [A composite score of the Behavior Assessment System for Children that combines the Attention Problems scale and the Hyperactivity scale.] |
| Zoo Locations Subtest | NCIT_C126882 | [A subtest of the Wechsler Preschool and Primary Scale of Intelligence, that measures visual as well as spatial dimension skills. Working within a specified time limit, the child views pictures of animals placed on a zoo layout and them must place the proper animal in the correct location.] |
| Digit Span Total Score | NCIT_C126883 | [The sum of the scores for the Digit Span Forward, Digit Span Backward, and Digit Span Sequencing scales of the Wechsler Intelligence Scale for Children.] |
| Twenty Two | NCIT_C126884 | [A natural number greater than twenty-one and less than twenty-three and the quantity that it denotes.] |
| Drug Hypersensitivity Syndrome | NCIT_C112208 | [A potentially life-threatening hypersensitivity reaction to a pharmacologic substance that is characterized by rash, lymphadenopathy, fever, hematologic abnormalities and involvement of one or more internal organs.] |
| Anticonvulsant Hypersensitivity Syndrome | NCIT_C112209 | [A form of drug hypersensitivity syndrome caused by anti-convulsants.] |
| Drug Induced Cutaneous Vasculitis | NCIT_C112204 | [A skin hypersensitivity reaction due to exposure to a pharmacologic substance that is characterized by raised purpuric lesions, red macules, hemorrhagic blisters and ulcerations.] |
| Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877 | NCIT_C112205 | [A pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. Pan-FGFR kinase inhibitor BAY1163877 inhibits the activities of FGFRs, which may result in the inhibition of both tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. FGFRs are a family of receptor tyrosine kinases, which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival.] |
| Autologous Tumor Cell Proteoliposome Chronic Lymphocytic Leukemia Vaccine | NCIT_C112206 | [An autologous chronic lymphocytic leukemia cancer vaccine consisting of patient-specific membrane proteins directly extracted from patient autologous tumor cells and incorporated into liposomes along with Interleukin 2 (IL-2) to produce membrane-patched proteoliposomes, with potential immunostimulating and antineoplastic activities. After subcutaneous injection of the autologous tumor cell proteoliposomes chronic lymphocytic leukemia vaccine, liposomes deliver the encapsulated tumor antigens into the cytosol of antigen presenting cells (APCs). Subsequently, the APCs process the antigens and present antigen-derived peptides to the immune system. This may enhance recognition of tumors by the immune system, and activate both cytotoxic CD8+ T cells and CD4+ helper T cells against tumor cells. IL-2 is incorporated into the vaccine to leverage its ability to expand activated T cells.] |
| Autologous-Cell Leukemia Vaccine | NCIT_C2023 | [An autologous therapeutic vaccine for the treatment of acute myelogenous leukemia. This vaccine is prepared from blood samples of patients following their first relapse. Tumor cells extracted from blood sample are modified with hapten, a process that makes the cells appear foreign to the patient's body and results in stimulating immune response against the cancer.] |
| Bivalent HPV16/18 Therapeutic Cervical Cancer Vaccine | NCIT_C112207 | [A bivalent human papillomavirus (HPV) therapeutic vaccine containing recombinant inactivated adenylate cyclase (CyaA) from Bordetella pertussis carrying a sequence encoding the E7 antigen of both HPV16 and 18, with potential immunostimulatory and antiviral properties. Upon administration of bivalent HPV16/18 therapeutic cervical cancer vaccine, the expressed proteins may activate cell-mediated immunity and induce both cytotoxic CD8+ T cells and CD4+ helper T cells against the target antigens HPV16-E7 and HPV18-E7, which leads to HPV viral clearance. Adenylate cyclase is a virulence factor of Bordetella pertussis. Its ability to bind to CD11b-expressing dendritic cells and deliver antigens directly to the cytosol allows the activation and induction of T-cell immunity. CyaA may also induce a B cell response.] |
| Telogen Effluvium | NCIT_C112200 | [A scalp hair loss condition characterized by excessive shedding of hair in the resting phase of growth, usually following a fever or major body stress.] |
| Polymorphous Light Eruption | NCIT_C112201 | [A red, edematous rash that occurs on areas of the skin with recent exposure to sunlight.] |