Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Histamine-1 Receptor Antagonist | NCIT_C29578 | [Any agent that binds to the histamine H1 receptor, thereby antagonizing histamine mediated allergic reactions, such as bronchoconstriction, vasodilation and up-regulated capillary permeability.] |
| Piclopastine | NCIT_C74583 | |
| Melengestrol Acetate | NCIT_C74577 | [A progestogen-like compound used as a cattle feed additive for its growth promoting effects and suppression of estrus (heat) in heifers. Critics have claimed that hormones used as growth promotants in cattle may cause breast cancer. (NCI)] |
| dl-alpha-Tocopherol | NCIT_C74578 | [A naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04)] |
| Anhydrous Lactose | NCIT_C74579 | |
| Disaccharide | NCIT_C68472 | |
| Fitzpatrick Skin Type V | NCIT_C74573 | [Skin which is brown and it burns very rarely when exposed to the sun. It is usually seen in people of Middle Eastern origin.] |
| Fitzpatrick Skin Type VI | NCIT_C74574 | [Skin which is dark brown or black and it never burns when exposed to the sun.] |
| Hyoscyamine Sulfate | NCIT_C74575 | [The sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. These inhibitory effects cause a decrease in saliva, bronchial mucus, gastric juices, and sweat. Furthermore, its inhibitory action on smooth muscle prevents bladder contraction and decreases gastrointestinal motility.] |
| Antimuscarinic Agent | NCIT_C29704 | [Natural or synthetic Antimuscarinic Agents inhibit acetylcholine neurotransmitter action at muscarinic receptors. Antimuscarinic drugs are used as antiarrhythmic, antiparkinson, antiasthmatic, and antispasmodic agents, as well as antidote of the natural mushroom alkaloid muscarine (Amanita muscaria) or to prevent parasympathetic stimulation at neuroeffector junctions. (NCI04)] |
| Pentetate Calcium Trisodium | NCIT_C74576 | [The trisodium salt form of calcium diethylene triamine pentaacetate (Ca-DTPA or pentetate calcium) with chelating activity. Upon administration, Ca-DTPA loses the Ca ion to form stable chelates with metal ions because DTPA has a higher affinity for heavy metal ions than for Ca ions. Specifically, this agent is able to bind to and form strong complexes with radioactive plutonium, americium, and cerium after internal contamination with any of these radionuclides thereby increasing their excretion.] |
| Metal Chelator | NCIT_C62357 | [An inorganic or organic molecule which binds metal ions. Metal chelators are frequently polydentate, indicating that they form multiple bonds with the metal ion, resulting in more stable coordination complexes.] |
| Telmesteine | NCIT_C74550 | |
| Mucolytic Agent | NCIT_C74536 | [Any agent that dissolves mucus, making it less thick and sticky. This makes it easier for the mucus to drain from the upper respiratory system, be removed through coughing, or be transported through the gastrointestinal (GI) tract.] |
| Teloxantrone Hydrochloride | NCIT_C74544 | [The hydrochloride salt of an anthrapyrazole antineoplastic antibiotic. Teloxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair, as well as RNA and protein synthesis] |
| Anthrapyrazole Antineoplastic Antibiotic | NCIT_C2107 | [A class of antibiotics related to the anthracycline antineoplastic antibiotics. The anthrapyrazole antibiotics intercalate into DNA and interact with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. These agents may also block cell cycle division. In the presence of electron donors, some anthrapyrazole antibiotics cause single-strand breaks in DNA via photosensitization by visible light. These agents are less cardiotoxic than doxorubicin. (NCI04)] |
| Calcium Pantothenate | NCIT_C74545 | [The calcium salt of the water-soluble vitamin B5, ubiquitously found in plants and animal tissues with antioxidant property. Pentothenate is a component of coenzyme A (CoA) and a part of the vitamin B2 complex. Vitamin B5 is a growth factor and is essential for various metabolic functions, including the metabolism of carbohydrates, proteins, and fatty acids. This vitamin is also involved in the synthesis of cholesterol, lipids, neurotransmitters, steroid hormones, and hemoglobin.] |
| Wheat | NCIT_C74546 | |
| Pazopanib | NCIT_C74547 | [A small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.] |
| Inguinofemoral Lymphadenectomy | NCIT_C74540 | [The surgical removal of superficial inguinal lymph nodes and deep femoral lymph nodes.] |