Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Australian	NCIT_C126535	[Denotes a person whose ancestry is in the country or continent of Australia.]
New Zealander	NCIT_C126536	[Denotes a person whose ancestry is in the country of New Zealand.]
South African	NCIT_C126530	[Denotes a person whose ancestry is in the country of South Africa.]
African	NCIT_C42331	[Denotes a person with ancestral origins are in any of the countries of Africa.]
Latin American	NCIT_C126531	[Denotes a person whose ancestry is in any of the countries of the Americas or the Caribbean where Spanish or Portuguese is spoken.]
South American	NCIT_C126532	[Denotes a person whose ancestry is in any of the countries of South America.]
CCND1 wt Allele	NCIT_C49519	[Human CCND1 wild-type allele is located within 11q13 and is approximately 13 kb in length. This allele, which encodes G1/S-specific cyclin-D1 protein, plays a role in the regulation of the cell cycle during the G1/S transition. Aberrant allelic expression caused by mutations, amplification and overexpression alters cell cycle progression. These abnormal alterations have been frequently identified in a variety of tumors and may contribute to tumorigenesis.]
CCND1 Gene	NCIT_C18021	[This gene plays a role in the regulation of mitotic events.]
CCNA2 wt Allele	NCIT_C49515	[Human CCNA2 wild-type allele is located within 4q25-q31 and is approximately 6 kb in length. This allele, which encodes cyclin-A2 protein, plays a role in cell cycle G1/S and G2/M transitions.]
CCNA2 Gene	NCIT_C20957	[This gene is involved in G1/S and G2/M transitions in the cell cycle.]
CCNB1 wt Allele	NCIT_C49516	[Human CCNB1 wild-type allele is located within 5q12 and is approximately 11 kb in length. This allele, which encodes G2/mitotic-specific cyclin-B1 protein, is involved in mitotic regulation during the G2/M transition of the cell cycle.]
CCNB1 Gene	NCIT_C26350	[This gene plays a regulatory role in mitosis.]
CCNB2 wt Allele	NCIT_C49517	[Human CCNB2 wild-type allele is located in the vicinity of 15q22.2 and is approximately 20 kb in length. This allele, which encodes G2/mitotic-specific cyclin-B2 protein, is involved in the regulation of the mitotic G2/M transition of the cell cycle. Aberrant allelic expression, resulting from different mechanisms, could contribute through an alteration of the spindle checkpoint, to the chromosomal instability observed in cancer.]
CCNB2 Gene	NCIT_C24268	[This gene is a mediator in cell cycle regulation.]
PTPN11 wt Allele	NCIT_C49518	[Human PTPN11 wild-type allele is located within 12q24 and is approximately 91 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 11 protein, is involved in the dephosphorylation of protein-tyrosine phosphates. The PTPN11 gene is associated with severe congenital neutropenia as well as several forms of leukemia.]
PTPN11 Gene	NCIT_C26337	[This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and gene transcription.]
PTPN1 wt Allele	NCIT_C49522	[Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 1 protein, is involved in the dephosphorylation of protein-tyrosine phosphates. Functional PTPN1 gene polymorphisms are associated with susceptibility to insulin resistance.]
PTPN1 Gene	NCIT_C24705	[This gene plays a role in the regulation of insulin signaling and inhibition of cell growth.]
CCND2 wt Allele	NCIT_C49523	[Human CCND2 wild-type allele is located in the vicinity of 12p13.32 and is approximately 32 kb in length. This allele, which encodes G1/S-specific cyclin D2 protein, plays a role in cell cycle regulation. Methylation of the gene generates allelic variants that are implicated in the pathogenesis of several cancers.]
CCND2 Gene	NCIT_C39596	[This gene is involved in the regulation of the G1/S phase of the cell cycle.]