Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
SFN Gene	NCIT_C24803	[This gene is involved in cell cycle regulation.]
PTPRR wt Allele	NCIT_C49539	[Human PTPRR wild-type allele is located within 12q15 and is approximately 283 kb in length. This allele, which encodes receptor-type tyrosine-protein phosphatase R protein, plays a role in the sequestration of inactive mitogen-activated protein kinases in the cytoplasm.]
PTPRR Gene	NCIT_C24715	[This gene is involved in neuronal growth and differentiation.]
CDC37 wt Allele	NCIT_C49544	[Human CDC37 wild-type allele is located in the vicinity of 19p13.2 and is approximately 12 kb in length. This allele, which encodes Hsp90 co-chaperone Cdc37 protein, plays a role in signal transduction and cell cycle progression.]
CDC37 Gene	NCIT_C24281	[This gene regulates the progression of cells through the G1 phase of the cell cycle.]
ADAM15 wt Allele	NCIT_C49545	[Human ADAM15 wild-type allele is located in the vicinity of 1q21.3 and is approximately 11 kb in length. This allele, which encodes ADAM15 protein, is involved in proteolysis that contributes to restructuring of the mesangial matrix.]
ADAM15 Gene	NCIT_C26544	[This gene is involved in the restructuring of the mesangial matrix.]
HSPA5 wt Allele	NCIT_C49546	[Human HSPA5 wild-type allele is located within 9q34 and is approximately 6 kb in length. This allele, which encodes 78 kDa glucose-regulated protein, plays a role in protein transport through the cell. HSPA5 allelic variants have been implicated in gastric tumor development.]
HSPA5 Gene	NCIT_C48837	[This gene is involved in cellular signal transduction.]
CASP10 wt Allele	NCIT_C49547	[Human CASP10 wild-type allele is located within 2q33-q34 and is approximately 46 kb in length. This allele, which encodes caspase-10 protein, plays a role in the activation of caspase-dependent apoptosis. Defects in the CASP10 gene are the cause of type II autoimmune lymphoproliferative syndrome.]
CASP10 Gene	NCIT_C28400	[This gene is involved in the activation of apoptosis.]
PTPRT wt Allele	NCIT_C49540	[Human PTPRT wild-type allele is located within 20q12-q13 and is approximately 1117 kb in length. This allele, which encodes receptor-type tyrosine-protein phosphatase T protein, is involved in the dephosphorylation of protein-tyrosine phosphates.]
PTPRT Gene	NCIT_C24716	[This gene plays a role in the control of motor axon guidance.]
DFFB wt Allele	NCIT_C126526	[Human DFFB wild-type allele is located in the vicinity of 1p36.3 and is approximately 28 kb in length. This allele, which encodes DNA fragmentation factor subunit beta protein, plays a role in the regulation of DNA fragmentation and chromosome condensation during apoptosis.]
DFFB Gene	NCIT_C126525	[This gene is involved in apoptosis.]
SKP2 wt Allele	NCIT_C49541	[Human SKP2 wild-type allele is located within 5p13 and is approximately 32 kb in length. This allele, which encodes S-phase kinase-associated protein 2, is involved in cell cycle arrest at the G1/S transition of the cell cycle. SKP2 variant alleles have been established as alleles that are causally involved in the pathogenesis of lymphomas.]
SKP2 Gene	NCIT_C24814	[This gene is involved in cell cycle regulation.]
DNA Fragmentation Factor Subunit Beta	NCIT_C126527	[DNA fragmentation factor subunit beta (338 aa, ~39 kDa) is encoded by the human DFFB gene. This protein is involved in the modulation of DNA fragmentation and chromosome condensation during apoptosis.]
Deoxyribonuclease	NCIT_C16499	[Enzymes that catalyze the hydrolytic cleavage of phosphodiester bond linkages in the DNA backbone. Deoxyribonucleases belong to a larger family of nucleases, which cleave DNA bases at various positions in the DNA backbone.]
TTK wt Allele	NCIT_C49542	[Human TTK wild-type allele is located within 6q13-q21 is approximately 38 kb in length. This allele, which encodes dual specificity protein kinase TTK protein, plays a role in cellular proliferation and is associated with kinetochore or centrosome functionality.]