Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Paranoid Type Schizophrenia	NCIT_C35006	[A subtype of schizophrenia characterized by prominent delusions (typically persecutory or grandiose) or hallucinations in the context of a relative preservation of cognitive functioning and affect.]
Apilimod Dimesylate Capsule	NCIT_C126661	[A capsule containing the dimesylate salt form of apilimod, an inhibitor of the class III PI kinase phosphatidylinositol-3-phosphate 5-kinase (PIKfyve), with potential antineoplastic and immunomodulatory activities. Upon oral administration of apilimod dimesylate capsule, apilimod selectively binds to and inhibits PIKfyve. The inhibition leads to disruption of PIKfyve-mediated signal transduction pathways and eventually inhibits tumor cell growth in PIKfyve-overexpressing tumor cells. Also, PIKfyve inhibition by apilimod inhibits the toll-like receptor (TLR)-induced production of various cytokines, including interleukin-12 (IL-12) and IL-23, thereby preventing IL-12/IL-23-mediated immune responses. PIKfyve, a lipid kinase dysregulated in various tumor types, plays a key role in TLR signaling and tumor cell migration, proliferation and survival.]
Antineoplastic Immunomodulating Agent	NCIT_C129820	[Any agent that is capable of modulating the immune system in order to exert antineoplastic effects. Antineoplastic immunomodulating agents either activate the immune system, restore certain immune system activators or abrogate immunosuppression.]
Metamyelocyte Count	NCIT_C74615	[The determination of the number of metamyelocytes present in a sample.]
Skin Itching at its Worst	NCIT_C126662	[A question about an individual's skin itching at its worst.]
Pappenheimer Body Count	NCIT_C74616	[The determination of the number of Pappenheimer bodies in a sample.]
Schwartz-Jampel Syndrome	NCIT_C35008	[A classification for rare genetic syndromes with an autosomal recessive pattern of inheritance. Clinical features include muscle stiffness and weakness, facial and skeletal abnormalities with joint contractures and short stature. Two types have been characterized: Schwartz-Jampel Syndrome type I (SJSI) and Schwartz-Jampel Syndrome type II (SJSII). SJSI is associated with a mutation of the HSPG2 gene on chromosome 1 and has been further characterized into two subtypes IA and IB. SJSIA is more common, less severe in presentation and is seen later in childhood than SJSIB. For both SJSI subtypes, prognosis is favorable as the main feature of muscle stiffness is slowly progressive, if at all, and is compatible with a normal life span. SJSII is apparent at birth, shares the same clinical profile and mutation in the LIFR gene noted in Stuve-Wiedemann Syndrome and is thus presumed to be the same disorder. In contrast to SJSI, its presentation is more severe and likelihood of survivability is much lower.]
Skin and/or Joint Tightening at its Worst	NCIT_C126663	[A question about an individual's skin and/or joint tightening at its worst.]
Pelger Huet Anomaly Measurement	NCIT_C74617	[The determination of the amount of Pelger Huet anomaly present in a sample.]
Sclerema Neonatorum	NCIT_C35009	[A diffuse hardening of skin and subcutaneous adipose tissue, associated with minimal inflammation without fat necrosis, that typically affects critically ill preterm neonates during the first week of life.]
Mouth Sensitivity at its Worst	NCIT_C126664	[A question about an individual's mouth sensitivity at its worst.]
Skin Pigmentation	NCIT_C35026	[The color of the skin as determined by the amount of melanin present.]
Pigmentation	NCIT_C38005	[Pigmentation; the coloring of the skin, hair, mucous membranes, and retina of the eye.]
Smallpox	NCIT_C35027	[A condition that is caused by infection with Variola, and that is characterized by small, raised bumps.]
Shoulder Dislocation	NCIT_C35020	[A dislocation of the shoulder joint.]
Joint Dislocation	NCIT_C26750	[An abnormal separation where two or more bones meet.]
Bunyaviridae	NCIT_C112028	[A family of negative-sense, enveloped RNA viruses that infect arthropods or rodents, but that can be transmitted to humans.]
Shoulder Fracture	NCIT_C35021	[A traumatic break in one or more of the bones that compose the shoulder joint.]
Sapovirus	NCIT_C112029	[A genus of non-enveloped viruses with a capsid with T=3 icosahedral symmetry, in the family Caliciviridae. The genome is composed of a linear, single-strand of positive sense RNA. Sapoviruses are found in humans and swine and cause gastroenteritis in humans.]
Caliciviridae	NCIT_C14304	[A family of single-stranded, non-segmented, positive-sense RNA viruses with a hexagonal/spherical capsid and no envelope. These viruses can be spread by the fecal-oral or respiratory route and infection typically leads to acute gastroenteritis.]