Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Roundabout Homolog 1	NCIT_C126590	[Roundabout homolog 1 (1651 aa, ~181 kDa) is encoded by the human ROBO1 gene. This protein is involved in neuronal development.]
CTSD wt Allele	NCIT_C49706	[Human CTSD wild-type allele is located in the vicinity of 11p15.5 and is approximately 11 kb in length. This allele, which encodes cathepsin D protein, plays a role in the degradation of intracellular proteins. Dysfunction of the CTSD gene is associated with malignant neoplasms of the breast.]
CTSD Gene	NCIT_C28406	[This gene plays a role in apoptosis and epidermal differentiation.]
CTSB wt Allele	NCIT_C49707	[Human CTSB wild-type allele is located within 8p22 and is approximately 24 kb in length. This allele, which encodes cathepsin B protein, is involved in the cleavage of lysosomal proteins. The CTSB gene is associated with Alzheimer's disease.]
CTSB Gene	NCIT_C28405	[This gene plays a role in the proteolytic processing of proteins involved in neuronal cellular processes.]
CTSH wt Allele	NCIT_C49708	[Human CTSH wild-type allele is located within 15q24-q25 and is approximately 28 kb in length. This allele, which encodes cathepsin H protein, plays a role in protein degradation within lysosomes. Overexpression of the CTSH gene is associated with prostate cancer.]
CTSH Gene	NCIT_C28463	[This gene is involved in the degradation of lysosomal proteins.]
CCL11 wt Allele	NCIT_C49709	[Human CCL11 wild-type allele is located within 17q21.1-q21.2 and is approximately 3 kb in length. This allele, which encodes eotaxin protein, plays a role in eosinophil chemotactic activity regulation.]
CCL11 Gene	NCIT_C24767	[This gene is involved in cell migration and chemotaxis.]
Medical History Dictionary	NCIT_C49702	[A reference source that provides meanings of words related to medical history.]
Test Product Added to Existing Treatment	NCIT_C49703	[An indication that an investigational drug or substance has been added to the existing treatment regimen.]
Dose Modification	NCIT_C54346	[Change, alteration, or adjustment of a dose specified in a treatment plan or/and administered to a patient.]
Common Terminology Criteria for Adverse Events	NCIT_C49704	[A standard terminology developed to report adverse events occurring in cancer clinical trials. Common terminology criteria for adverse events (CTCAE) are used in study adverse event summaries and Investigational New Drug reports to the Food and Drug Administration. The CTCAE contain a grading scale for each adverse event term representing the severity of the event.]
Adverse Event Classification	NCIT_C48276	[The systematic arrangement of adverse events based on common characteristics such as properties and outcomes.]
Severity/Intensity Scale for Adverse Events	NCIT_C49705	[A scale that defines the degree or state of disease existing in a patient as a result of the occurrence of an adverse event.]
CTSL wt Allele	NCIT_C49710	[Human CTSL wild-type allele is located within 9q21-q22 and is approximately 5 kb in length. This allele, which encodes cathepsin L protein, is involved in lysosomal protein degradation.]
CTSL Gene	NCIT_C28461	[This gene is involved in intracellular protein catabolism.]
CTSZ wt Allele	NCIT_C49711	[Human CTSZ wild-type allele is located within 20q13 and is approximately 12 kb in length. This allele, which encodes cathepsin Z protein, plays a role in the release of C-terminal amino acids from lysosomal proteins.]
CTSZ Gene	NCIT_C24320	[This gene plays a role in intracellular protein catabolism.]
CCL13 wt Allele	NCIT_C49712	[Human CCL13 wild-type allele is located in the vicinity of 17q11.2 and is approximately 2 kb in length. This allele, which encodes C-C motif chemokine 13 protein, plays a role in immune cell chemotaxis and signal transduction. CCL13 allelic variants may also be involved in atherosclerosis.]