Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Not Used	NCIT_C69062	[Not employed or utilized.]
Missing Value Reason	NCIT_C48655	[A specific reason explaining why a meaningful value is not available. A meaningful value answers the question posed by a Data Element Concept. In contrast, a Missing Value Reason answers the implicit question "Why is there no 'meaningful' value?", when there is none.]
Throat Spray Dosage Form	NCIT_C69063	[A spray intended for administration to the mucosa of the throat.]
Spray Dosage Form	NCIT_C42989	[A solution or suspension composed of active and/or inert ingredient(s) in oil or water, typically dispensed from an atomizer or nebulizer.]
Nasal Dosage Form	NCIT_C69064	[A substance intended for administration in the nares.]
Rindopepimut	NCIT_C69076	[A cancer vaccine consisting of a human epidermal growth factor receptor variant III (EGFRvIIi)-specific peptide conjugated to the non-specific immunomodulator keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. Vaccination with rindopepimut may elicit a cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing EGFRvIII. EGFRvIII, a functional variant of EGFR that is not expressed in normal tissues, was originally discovered in glioblastoma multiforme (GBM) and has also been found in various other cancers such as breast, ovarian, metastatic prostate, colorectal, and head and neck cancers. EGFRvIII contains an 83 amino acid deletion in its extracellular domain and has been shown to transform NIH/3T3 mouse embryonic fibroblast cells in vitro.]
Antineoplastic Vaccine	NCIT_C1663	[A type of vaccine that prevents or treats cancer.]
Planned Activity Repeat Duration	NCIT_C94000	[The period of time over which the planned activity is repeated.]
Repeat Duration	NCIT_C93647	[The period of time over which the event or activity is repeated.]
Anti-Hemophilia Factor Unit	NCIT_C69077	[One international unit of antihemophilic activity is equivalent to the quantity of antihemophilic factor (Factor VIII) present in 1 mL of normal human plasma.]
Unit of Biological and Biochemical Measurement	NCIT_C48463
Planned Activity Repeat Frequency Code	NCIT_C94001	[A coded value specifying the number of occurrences of a planned activity within a given time period.]
Repeat Frequency Code	NCIT_C93648	[A coded value specifying the number of occurrences of an event within a given time period.]
Net Weight	NCIT_C69078	[The weight of the content in a container without the weight of the container or any other packaging material.]
Weight	NCIT_C25208	[The vertical force exerted by a mass as a result of gravity.]
Planned Activity Repeat Frequency Ratio	NCIT_C94002	[A ratio representing the number of occurrences of a planned activity within a given time period.]
Repeat Frequency Ratio	NCIT_C93649	[A ratio representing the number of occurrences of an event within a given time period.]
Polymeric Camptothecin Prodrug XMT-1001	NCIT_C69079	[A polymeric prodrug of camptothecin (CPT) with potential antineoplastic activity. Polymeric camptothecin prodrug XMT-1001 consists of CPT conjugated to the 60-70 kDa, inert, bio-degradable, hydrophilic copolymer poly[1-hydroxymethylene hydroxymethyl formal] (PHF). Through a dual-phase, non-enzymatic release mechanism, CPT is first released in plasma from XMT-1001 as the lipophilic prodrugs CPT-SI (a succinimidoglycinate derivative) and CPT-SA (a succinamidoyl glycinate derivative), which are then hydrolyzed within tissues to release the lactone form of CPT. CPT inhibits the catalytic activity of DNA topoisomerase I, thereby inhibiting DNA replication and inducing apoptosis. This agent may exhibit a more favorable pharmacokinetic profile than other agents in the same class.]
Topoisomerase-I Inhibitor	NCIT_C1904	[Any substance that inhibits topoisomerase-I, a topoisomerase that relieves torsional stress in a DNA molecule by cutting only one strand of the DNA double helix. Inhibition of topoisomerase-I causes DNA damage, inhibition of DNA replication, and apoptosis.]
Planned Activity Repeat Quantity	NCIT_C94003	[The number of times the planned activity occurs.]