Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
CCL14 Gene	NCIT_C24769	[This gene is involved in the regulation of cellular calcium levels and in the proliferation of monocytes.]
FURIN wt Allele	NCIT_C49715	[Human FURIN wild-type allele is located in the vicinity of 15q26.1 and is approximately 15 kb in length. This allele, which encodes furin protein, plays a role in the cleavage of proteins containing paired basic amino-acid residues to release mature proteins from their precursor proteins.]
FURIN Gene	NCIT_C18603	[This gene plays a role in cell-cell signaling and signal transduction.]
KLK11 wt Allele	NCIT_C49716	[Human KLK11 wild-type allele is located within 19q13.3-q13.4 and is approximately 6 kb in length. This allele, which encodes kallikrein-11 protein, is involved in the proteolytic cleavage of substrates for both kallikrein and trypsin.]
KLK11 Gene	NCIT_C43294	[This gene is involved in protein degradation.]
CCL17 wt Allele	NCIT_C49720	[Human CCL17 wild-type allele is located within 16q13 and is approximately 11 kb in length. This allele, which encodes C-C motif chemokine 17 protein, plays a role in T lymphocyte chemomotaxis; which subsequently affects inflammatory processes in thymic T cell development, and the trafficking and activation of mature T cells.]
CCL17 Gene	NCIT_C24771	[This gene is involved in several processes such as T cell development in the thymus and mature T cell regulation.]
KLK3 wt Allele	NCIT_C49721	[Human KLK3 wild-type allele is located in the vicinity of 19q13.41 and is approximately 6 kb in length. This allele, which encodes prostate-specific antigen protein, plays a role in the liquefaction of seminal coagulum via hydrolysis of semenogelin-1. An allelic variant of KLK3 is associated with increased risk of prostate cancer onset in males under the age of 67. Overexpression of the KLK3 gene is strongly associated with prostate cancer.]
KLK3 Gene	NCIT_C26585	[This gene is involved in the hydrolysis of high molecular mass seminal vesicle protein, resulting in the liquefaction of seminal coagulum.]
ADAM17 wt Allele	NCIT_C49722	[Human ADAM17 wild-type allele is located within 2p25 and is approximately 66 kb in length. This allele, which encodes ADAM17 protein, is involved in the cleavage of membrane-bound cell-surface proteins to release their mature soluble forms.]
ADAM17 Gene	NCIT_C48217	[This gene plays a role in the cleavage of membrane proteins, resulting in the release of their extracellular domains from cells.]
CCL18 wt Allele	NCIT_C49723	[Human CCL18 wild-type allele is located in the vicinity of 17q11.2 and is approximately 7 kb in length. This allele, which encodes C-C motif chemokine 18 protein, is involved in the chemotactic regulation of naive T cells, CD4+ and CD8+ T cells, and nonactivated lymphocytes involved in inflammatory processes. CCL18 allele may also be involved in B cell migration into lymph node follicles as well as humoral and cell-mediated immunity.]
CCL18 Gene	NCIT_C24772	[This gene plays a role in the modulation of immune responses.]
ROBO1 Gene	NCIT_C126588	[This gene is involved in neuroblast migration and axon guidance.]
ROBO1 wt Allele	NCIT_C126589	[Human ROBO1 wild-type allele is located in the vicinity of 3p12 and is approximately 1170 kb in length. This allele, which encodes roundabout homolog 1 protein, plays a role in both axon guidance and neuroblast migration.]
NIT1 wt Allele	NCIT_C126584	[Human NIT1 wild-type allele is located within 1q21-q22 and is approximately 7 kb in length. This allele, which encodes nitrilase homolog 1 protein, is involved in both the catabolism of nitrogen compounds and the regulation of apoptosis.]
1q21-q22	NCIT_C13704	[A chromosome band present on 1q]
Nitrilase Homolog 1	NCIT_C126585	[Nitrilase homolog 1 (327 aa, ~38 kDa) is encoded by the human NIT1 gene. This protein plays a role in both nitrogen compound metabolism and the positive regulation of apoptosis.]
Hydrolase	NCIT_C16701	[Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage; e.g., esterases, phosphatases, nucleases, peptidases. SYN hydrolyzing enzymes.]
Eligible	NCIT_C126586	[Satisfying the appropriate conditions for inclusion.]