Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Immunologic Factor Interaction	NCIT_C40512	[Immunologic Factor Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction and often spatial complementarity with antibody or cytokine proteins that affect immune functions, immune responses, or inflammation.]
FAMS - I Feel Weak All Over	NCIT_C112561	[Functional Assessment of Multiple Sclerosis (FAMS) Symptoms: I feel weak all over.]
FAMS - I Have Pain in My Joints	NCIT_C112562	[Functional Assessment of Multiple Sclerosis (FAMS) Symptoms: I have pain in my joints.]
Interleukin-3/Thiotepa	NCIT_C15560
Thiotepa	NCIT_C875	[A polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity. Upon administration, thiotepa is converted into highly reactive ethylenimine groups, which covalently bind to nucleophilic groups in DNA and demonstrate a preference for the N7 position of guanine bases. This induces crosslinking of alkylated guanine bases in double-stranded DNA, interferes with both DNA replication and cell division, and results in both the induction of apoptosis and the inhibition of cell growth.]
Recombinant Interleukin-3	NCIT_C588	[A recombinant form of interleukin-3, a cytokine produced by activated T-cells and mast cells involved in intercellular communication, hematopoiesis, and inflammation. IL-3 binds and activates specific receptors on hematopoietic cells and in the nervous system, triggering expression of specific genes via the Ras signaling pathway and through Jak2 activation. This agent stimulates the proliferation of pluripotent hematopoietic progenitor cells.]
Cancer Prevention Intervention	NCIT_C15561
Interleukin-3/Melphalan	NCIT_C15562
Interleukin-3/Zidovudine	NCIT_C15563
Zidovudine	NCIT_C947	[A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. (NCI04)]
Prior Adjuvant Chemotherapy	NCIT_C15564
Prior Biologic Therapy	NCIT_C15452	[Previous biologic therapy administered as treatment.]
Prior Adjuvant Endocrine Therapy	NCIT_C15565	[An indication that an individual has been previously treated with endocrine/hormonal therapy following surgery.]
Prior Hormone Therapy	NCIT_C16175	[An indication that an individual has been previously treated with hormonal therapy.]
Neoadjuvant Study	NCIT_C15566
Adjuvant Study	NCIT_C15446	[A study performed secondary to and in support of a primary or base study in order to support, enhance, or expand upon its results or findings.]
Screening for Gastric Cancer	NCIT_C15567
Antiangiogenesis Therapy	NCIT_C15568	[A therapeutic regimen that uses synthetic compounds or natural substances to prevent the development of new blood vessels.]
Growth Factor Antagonist Therapy	NCIT_C15510
Free Radical Scavenging	NCIT_C40503	[Free Radical Scavenging involves interference with, or restraint of, production, by ready combination with, chemically unstable, short half-life and highly reactive molecules carrying at least one unpaired or 'free' electron in the outermost electron shell. Appropriating electron(s) from a nearby molecule and damaging that molecule by altering the electron number in its outermost electron shell, Free Radicals produce tissue damage.]