Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
EF-1 Peptide	NCIT_C49063	[A synthetic peptide derived from the protein ESW/FLI1 type 1 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-1 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 1 fusion protein.]
EF-2 Peptide	NCIT_C49064	[A synthetic peptide derived from the protein ESW/FLI1 type 2 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-2 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 2 fusion protein.]
Organizational Branch	NCIT_C49065	[An administrative division of some larger or more complex organization.]
Division	NCIT_C85531	[An administrative unit within a government, academic organization or business.]
Cellular Pleomorphism	NCIT_C49066
FAMS - Bothered by Muscle Spasms	NCIT_C112608	[Functional Assessment of Multiple Sclerosis (FAMS) Additional Concerns: I am bothered by muscle spasms.]
Public	NCIT_C49060	[Not private; open to or concerning the people as a whole.]
KFSS - Pyramidal Functions	NCIT_C112609	[Kurtzke Functional Systems Scores (KFSS) Pyramidal functions.]
Ridaforolimus	NCIT_C49061	[A small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potential antitumor activity. Ridaforolimus binds to and inhibits the mammalian target of rapamycin (mTOR), which may result in cell cycle arrest and, consequently, the inhibition of tumor cell growth and proliferation. Upregulated in some tumors, mTOR is a serine/threonine kinase involved in regulating cellular proliferation, motility, and survival that is located downstream of the PI3K/Akt signaling pathway.]
mTOR Inhibitor	NCIT_C2201	[Any substance that inhibits mammalian target of rapamycin (mTOR or FK506 binding protein 12-rapamycin associated protein 1 (FRAP1)), a serine/threonine protein kinase that is active in the control of cell growth, cell proliferation, and cell motility. Inhibition of mTOR can inhibit cell proliferation.]
Serine/Threonine-Protein Kinase mTOR	NCIT_C38929	[Serine/threonine-protein kinase mTOR (2549 aa, ~289 kDa) is encoded by the human MTOR gene. This protein is involved in protein phosphorylation, signaling and cell growth.]
gp100 Antigen/Incomplete Freund's Adjuvant/interleukin-2	NCIT_C15635
gp100 Antigen/Incomplete Freund's Adjuvant/Interleukin-12	NCIT_C15636
gp100 Antigen/interleukin-2/MART-1 Antigen	NCIT_C15637
Genetic Testing for Cancer Risk	NCIT_C15638	[Analyzing DNA to look for a genetic alteration that may indicate an increased risk for developing a cancer.]
Genetic Testing	NCIT_C15709	[The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder.]
Level of Evidence	NCIT_C15639	[A formal ranking system of the strength of evidence linked to a reported result.]
Clinical Testing	NCIT_C15791	[Small-scale testing (usually on SBIRs) of new technology in a small group of patients or normal volunteers. Does not meet the rigorous criteria of a clinical trial.]
Grade 4 Otitis Externa, CTCAE	NCIT_C146020	[Life-threatening consequences; urgent intervention indicated]
Otitis Externa, CTCAE	NCIT_C143719	[A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage.]