Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Transmembrane Protein	NCIT_C16747	[A protein that is an integral membrane protein with a transmembrane region.]
Integrin Binding	NCIT_C25864	[A process that involves the binding of an integrin to one of its ligands, including fibronectin, vitronectin, collagen and laminin. These interactions are involved in attachment of the cell to the extracellular matrix and transduction of signals related to cell growth, division, differentiation, survival and apoptosis.]
Neuron-Specific Enolase Positive Neoplastic Cells Present	NCIT_C60707	[An immunophenotypic test result indicating positive staining of neoplastic cells for neuron-specific enolase.]
ENO2 Positive	NCIT_C162084	[An indication that ENO2 expression has been detected in a sample.]
Binary Object	NCIT_C60708	[An object that includes binary encoding of a picture, photo, image, graphic, sound, or video.]
Computer Programming Object	NCIT_C45974	[In object-oriented programming, an object is a self-contained entity that consists of both data and procedures to manipulate the data.]
Appendix Neuroendocrine Neoplasm	NCIT_C60709	[A neoplasm with neuroendocrine differentiation that arises from the appendix. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade).]
Digestive System Neuroendocrine Neoplasm	NCIT_C27721	[A neoplasm with neuroendocrine differentiation arising from the digestive system. It includes neuroendocrine tumors (well-differentiated endocrine tumors or carcinoid tumors and well differentiated endocrine carcinomas) and neuroendocrine carcinomas (poorly differentiated neuroendocrine carcinomas, small cell carcinomas, and large cell neuroendocrine carcinomas).]
Appendix Neoplasm	NCIT_C4434	[A benign or malignant neoplasm involving the appendix.]
Metastasis Suppressor Protein	NCIT_C21140	[Proteins involved in the inhibition of tumor cell metastasis.]
Protein, Organized by Function	NCIT_C20027	[Organizing term for the Proteins tree]
Metastasis Suppressor Gene	NCIT_C20762	[A cancer gene that plays a role in the suppression of metastasis, a process whereby cancer spreads from one part of the body to another.]
Metastasis Suppression	NCIT_C20764	[Metastasis Suppression involves interference or restraint of the spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor (NCI)]
Metastasis-Suppressor KiSS-1	NCIT_C21141	[Metastasis-suppressor KiSS-1 (138 aa, ~15 kDa) is encoded by the human KISS1 gene. This protein plays a role in cytoskeleton rearrangement and metastasis suppression.]
KISS1 Gene Product	NCIT_C136718	[A protein encoded by the KISS1 gene.]
Pancreas	NCIT_C12393	[An organ behind the lower part of the stomach that is the shape of a fish and about the size of a hand. It is a compound gland composed of both exocrine and endocrine tissues. The endocrine pancreas makes insulin so that the body can use glucose (sugar) for energy. The exocrine pancreas makes enzymes that help the body digest food. Spread all over the pancreas are areas called the Islets of Langerhans. The cells in these areas each have a special purpose. The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin. There are also PP cells and D1 cells, about which little is known.]
Placenta	NCIT_C13272	[An organ present in some vertebrates during embryonic gestation that surrounds the fetus and provides it with nutrients and oxygen, facilitates gas and waste exchange between the fetus and mother, and provides parasitic cloaking from the mother's immune system by excretion of neurokinin B.]
Kidney	NCIT_C12415	[One of the two bean-shaped organs located on each side of the spine in the retroperitoneum. The right kidney is located below the liver and the left kidney below the diaphragm. The kidneys filter and secret the metabolic products and minerals from the blood, thus maintaining the homeostasis. On the superior pole of each kidney there is an adrenal gland. Each kidney and adrenal gland is surrounded by fat.]
Breast Carcinoma	NCIT_C4872	[A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla.]
Melanoma	NCIT_C3224	[A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.]