Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Prostatic Secretion Alteration	NCIT_C40937	[Prostatic Secretion Alteration involves a qualitative change in existing activities involved in release into seminal fluid of acid phosphatase, citric acid, and proteolytic enzymes that liquefy coagulated semen, from the accessory sex gland of the male reproductive system that surrounds the neck of the bladder and urethra (prostate gland).]
Prostatic Size Alteration	NCIT_C40938	[Prostatic Size Alteration involves a change in the dimensions of the accessory sex gland (prostate gland) of the male reproductive system that surrounds the neck of the bladder and urethra and secretes into seminal fluid acid phosphatase, citric acid, and proteolytic enzymes that liquefy coagulated semen.]
Resectable Pancreatic Ductal Adenocarcinoma	NCIT_C151995	[Pancreatic ductal adenocarcinoma amenable to surgical resection.]
Resectable Pancreatic Adenocarcinoma	NCIT_C156906	[Pancreatic adenocarcinoma that is amenable to surgical resection.]
Pancreatic Ductal Adenocarcinoma	NCIT_C9120	[An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are usually over 50 years of age. Microscopically it is characterized by the presence of glandular (ductal) differentiation and desmoplastic stroma formation. Signs and symptoms include pain, loss of weight, and jaundice. It grows rapidly and is usually detected after it has metastasized to other anatomic sites. The prognosis is usually poor.]
GALNT12 Gene	NCIT_C151996	[This gene plays a role in O-linked protein glycosylation.]
GALNT12 wt Allele	NCIT_C151997	[Human GALNT12 wild-type allele is located in the vicinity of 9q22.33 and is approximately 42 kb in length. This allele, which encodes polypeptide N-acetylgalactosaminyltransferase 12 protein, is involved in O-linked glycosylation of protein substrates. Mutation of the gene is associated with an increased risk of colorectal cancer.]
Polypeptide N-Acetylgalactosaminyltransferase 12	NCIT_C151998	[Polypeptide N-acetylgalactosaminyltransferase 12 (581 aa, ~67 kDa) is encoded by the human GALNT12 gene. This protein plays a role in catalyzing the transfer of an N-acetyl-D-galactosamine (GalNAc) residue to a serine or threonine residue on a protein substrate.]
Mixed Phenotype Acute Leukemia, B/T/Myeloid, Not Otherwise Specified	NCIT_C151991	[A very rare mixed phenotype acute leukemia, not otherwise specified in which the blasts show evidence of trilineage (B-cell, T-cell, and myeloid lineage) assignment. (WHO 2017)]
Mixed Phenotype Acute Leukemia, B/T, Not Otherwise Specified	NCIT_C151992	[A very rare mixed phenotype acute leukemia, not otherwise specified in which the blasts show clear-cut evidence of both B-cell and T-cell lineage. (WHO 2017)]
Ovulation Alteration	NCIT_C40930	[Ovulation Alteration consists of a change in the quality of the existing state of processes involved in release of an egg from the ovary. Mechanisms of alteration include increased or decreased secretion of Luteinizing Hormone or Follicle Stimulating Hormone.]
Locally Advanced Pancreatic Ductal Adenocarcinoma	NCIT_C151993	[A pancreatic ductal adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.]
Locally Advanced Pancreatic Adenocarcinoma	NCIT_C156269	[A pancreatic adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.]
Metastatic Pancreatic Ductal Adenocarcinoma	NCIT_C158960	[An adenocarcinoma that arises from the exocrine pancreatic ducts and has metastasized to other anatomic sites.]
STAT3 Inhibitor DSP-0337	NCIT_C151994	[An orally administered prodrug of napabucasin, a small molecule cancer stemness inhibitor with potential antineoplastic activity. Upon administration, DSP-0337 is converted to its active form, napabucasin. Napabucasin targets and inhibits signal transducer and activator of transcription 3 (STAT3), thereby preventing STAT-3-mediated signaling. The STAT3 pathway is overly active in many cancer types and is implicated in cancer stem cell-mediated growth, recurrence and resistance to conventional chemotherapies.]
Cyclin-dependent Kinase Inhibitor PF-06873600	NCIT_C151988	[An orally bioavailable, cyclin dependent kinase (CDK) inhibitor, with potential antineoplastic activity. Upon administration, PF-06873600 selectively targets, binds to and inhibits the activity of CDKs. Inhibition of these kinases leads to cell cycle arrest, an induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are ATP-dependent serine/threonine kinases that are important regulators of cell cycle progression and proliferation and are frequently overexpressed in tumor cells.]
Ice Pack	NCIT_C151989	[A container filled with frozen material that retains its temperature for an extended period.]
Radiometry (Microwave)	NCIT_C15980	[The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by scintillation counting.]
Radiation Dosimetry	NCIT_C15312	[The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by scintillation counting.]
Supportive Cancer Chemotherapy	NCIT_C15981	[Treatment designed to improve the health of a chemotherapy patient but that does not directly affect the tumor.]