Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Carton Dosing Unit | NCIT_C54702 | [A dosing unit equal to the amount of active ingredient(s) contained in a carton.] |
| FTC Mouse | NCIT_C15138 | |
| Cup Dosing Unit | NCIT_C54703 | [A dosing unit equal to the amount of active ingredient(s) contained in a cup.] |
| PC/CpbU Mouse | NCIT_C15139 | |
| 1-Nitrobenzo[a]pyrene trans-7,8-Dihydrodiol | NCIT_C29780 | |
| Benzo[a]pyrene trans-7,8-Dihydrodiol | NCIT_C29809 | [A polycyclic aromatic hydrocarbon and metabolite of benzo(a)pyrene with potent cytotoxic and mutagenic properties. Benzo(a)pyrene-trans-7,8-dihydrodiol is an intermediate in the conversion of benzo(a)pyrene to the highly potent mutagen and carcinogen benzopyrene diol epoxide via cytochrome P450 CYP1A1.] |
| 1-Nitropyrene | NCIT_C29781 | [A synthetic, light sensitive, yellow crystalline solid that is practically insoluble in water and soluble in diethyl ether, acetone, ethanol, benzene and toluene. It is not used for any commercial applications and is used only for research purposes, principally as a marker for exposure to nitro-polycyclic aromatic hydrocarbons from diesel exhaust. When heated to decomposition, 1-nitropyrene emits toxic fumes of nitrogen oxides. This compound is found in particulate emissions from combustion products, of which diesel exhaust is the principle source. The primary route of potential human exposure to 1-nitropyrene is inhalation. This compound is one of the most abundant mononitroarenes detected in ambient air. Occupational exposure to 1-nitropyrene occurs primarily in workers exposed to diesel engine exhaust in the transport industry. It is reasonably anticipated to be a human carcinogen. (NCI05)] |
| Nitroarene Carcinogen | NCIT_C45182 | [Potentially cancer-causing compound containing carbon and hydrogen in the form of an unsaturated, usually hexagonal, ring structure with one or more nitro-group(s), -NO2, attached to one or more aromatic ring(s). The compounds can be single ring, or double, triple, or multiple fused rings. These compounds are normally found in particulate emissions from many combustion sources, like diesel exhaust. (NCI05)] |
| 19-Norprogesterone | NCIT_C29782 | [A steroid progestin derivative with antigonadotropic activity. 19-nor-Progesterone decreases luteinizing hormone (LH) and follicle stimulatory hormone (FSH) secretion, which are effects likely mediated through the binding of this agent to the progesterone receptor. The antigonadotropic activity of this hormone results in reinforcement of its antiestrogenic activity, allowing treatment of the clinical hyper-estrogenic symptoms of peri-menopause without negative metabolic or hemostatic effects. 19-nor-Progesterone, in addition to its inhibitory effect on ovulation, induces changes in the endometrium, rendering it resistant to implantation, and in the cervical mucus, rendering it hostile to spermatozoa migration. This agent is also a potent mineralocorticoid. (NCI04)] |
| Androsterone | NCIT_C29783 | [A steroid metabolite derived from sex hormones, which displays weak androgenic properties. In testes is formed from progesterone. Androsterone sulfate is clinically recognized as one of the major androgen metabolites found in urine, in males and females. It is made in the liver from the metabolism of testosterone. Androsterone glucuronide, a dihydrotestosterone metabolite, is present in serum. Androsterone is a weak anabolic hormone. (NCI04)] |
| Therapeutic Androgen | NCIT_C243 | [A synthetic or animal-derived hormone that is chemically or functionally similar or identical to endogenous androgen with potential use in therapeutic applications.] |
| Bovine Pituitary Extract | NCIT_C29784 | [A substance isolated from the pituitary glands of cattle which contains a variety of proteins, hormones, and growth factors. Bovine pituitary extract is used in research as a mitogenic supplement in the cell culture of various epithelial and endothelial cell lines. (NCI04)] |
| Recombinant Adenovirus-Cre Recombinase | NCIT_C29785 | |
| Recombinant Adenovirus-LacZ | NCIT_C29786 | |
| 1,2-Dimethylhydrazine | NCIT_C29787 | [A compound used experimentally to induce tumors in animal models of carcinogenesis. In mice and rats, 1,2-dimethylhydrazine may induce carcinogenesis through deregulation of the cell cycle. This agent primarily induces gastrointestinal and vascular tumors. 1,2-Dimethylhydrazine may be found in small amounts in the environment due to its use in industry and agriculture. (NCI04)] |
| Organo-nitrogen Carcinogen | NCIT_C45176 | [An organic carcinogen having a C-N bond incorporated in its structure. (NCI05)] |
| 1,2-Dimethylhydrazine Dihydrochloride | NCIT_C29788 | [The chloride salt of a compound used experimentally to induce tumors in animal models of carcinogenesis. In mice and rats, 1,2-dimethylhydrazine may induce carcinogenesis through deregulation of the cell cycle. This agent primarily induces gastrointestinal and vascular tumors. 1,2-Dimethylhydrazine may be found in small amounts in the environment due to its use in industry and agriculture. (NCI04)] |
| 1,2,5,6-Dibenzanthracene | NCIT_C29789 | |
| Allergic Rhinitis Including Sneezing Nasal Stuffiness Postnasal Drip, CTCAE | NCIT_C54737 | |
| Adverse Event Associated with Allergy and Immunology | NCIT_C53782 |