Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Methotrexate-Associated Lymphoma	NCIT_C150678	[A non-Hodgkin or Hodgkin lymphoma that develops in patients who are immunosuppressed with methotrexate.]
Nodular Lymphocyte Predominant Hodgkin Lymphoma	NCIT_C7258	[A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)]
Recurrent Nodular Lymphocyte Predominant Hodgkin Lymphoma	NCIT_C7259	[The reemergence of nodular lymphocyte predominant Hodgkin lymphoma after a period of remission.]
Recurrent Hodgkin Lymphoma	NCIT_C4937	[The reemergence of Hodgkin lymphoma after a period of remission.]
Grade 5 Osteonecrosis, CTCAE	NCIT_C146460	[Death]
Nicardipine Hydrochloride	NCIT_C29840	[The hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator. (NCI04)]
Nickel Subsulfide	NCIT_C29841	[Exposure to inorganic carcinogenic Nickel Subsulfide, an atmospheric pollutant primarily generated by industries that manufacture lithium batteries, results in inflammation, hyperplasia, and fibrosis in the lungs and olfactory epithelium. (NCI04)]
Nimesulide	NCIT_C29842	[A nonsteroidal arylsulfonamide with anti-inflammatory properties. Nimesulide inhibits the cyclooxygenase-mediated conversion of arachidonic acid to pro-inflammatory prostaglandins. Modestly selective for COX-2, this agent binds to the enzyme, thereby inactivating it. Nimesulide may inhibit some carcinogenic COX-2-related carcinogenic effects on xenobiotic metabolism, apoptosis, immune surveillance and angiogenesis (overexpressed COX-2 in tumor epithelial cells enhances production of vascular growth factors and the formation of capillary-like networks). (NCI04)]
Nitrogen Dioxide	NCIT_C29843	[Found in the atmosphere as a key ingredient in photochemical formation of smog and acid rain, Nitrogen Dioxide is a poisonous gas that forms during combustion. Toxic at high concentrations, it reacts with moisture in the air to form nitric acid, highly corrosive and hazardous to plants and animals. (NCI04)]
Week	NCIT_C29844	[Any period of seven consecutive days.]
Age Unit	NCIT_C50400	[Those units of time that are routinely used to express the age of a person or thing.]
o-Aminoazotoluene	NCIT_C29845	[A synthetic organic azo dye used mainly in experimental research, carcinogenic o-Aminoazotoluene induces hepatomas, lung tumors, bladder tumors, and lung hemangioendotheliomas in animals when administered in the diet. (NCI04)]
Carcinogenic Aromatic Amine	NCIT_C45178	[Potentially cancer-causing compound containing amine with an aromatic ring substituted for one or more of its hydrogen atoms, i.e., -NH2, -NH- or nitrogen group(s) attached to an aromatic hydrocarbon, whose structure usually contains one or more benzene rings. This group includes many industrial and tobacco carcinogens. (NCI05)]
Month	NCIT_C29846	[One of the 12 divisions of a year as determined by a calendar. It corresponds to the unit of time of approximately to one cycle of the moon's phases, about 30 days or 4 weeks.]
DNA Topology Regulation	NCIT_C29836	[DNA Topology Regulation involves DNA topoisomerases that catalyze essential DNA transaction processes, including DNA strand scission, manipulation, and rejoining, in order to attain a balanced topology of the genome. Contrasting activities of DNA topoisomerase I and DNA gyrase result in the maintenance of DNA topological homeostasis. (NCI)]
Grade 5 Pancreatic Fistula, CTCAE	NCIT_C146469
Zinc-Finger Protein RFP	NCIT_C29837	[Zinc finger protein RFP (513 aa, ~58 kDa) is encoded by the human TRIM27 gene. This protein is involved in the modulation of both gene transcription and apoptosis.]
E3 Ubiquitin-Protein Ligase TRIM13	NCIT_C29838	[E3 ubiquitin-protein ligase TRIM13 (407 aa, ~47 kDa) is encoded by the human TRIM13 gene. This protein plays a role in regulating the degradation of endoplasmic reticulum proteins.]
Naphthalene	NCIT_C29839	[A white, volatile, solid polycyclic hydrocarbon with a strong mothball odor. Naphthalene is obtained from either coal tar or petroleum distillation and is primarily used to manufacture phthalic anhydride, but is also used in moth repellents. Exposure to naphthalene is associated with hemolytic anemia, damage to the liver and neurological system, cataracts and retinal hemorrhage. Naphthalene is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing laryngeal and colorectal cancer. (NCI05)]
Methotrexate-Associated Peripheral T-Cell Lymphoma	NCIT_C7252	[A peripheral T-cell lymphoma that develops in patients who are immunosuppressed with methotrexate.]