All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Benign Ovarian Serous Tumor | NCIT_C7313 | [A non-metastasizing neoplasm that arises from the ovary and is characterized by the presence of neoplastic epithelium that resembles the epithelium of the fallopian tube. It includes serous cystadenoma, serous adenofibroma, serous cystadenofibroma, and surface papilloma.] |
| Serous Surface Papilloma | NCIT_C4181 | [A non-invasive papillary serous epithelial neoplasm usually arising from the ovary.] |
| Tricaprylin | NCIT_C29861 | |
| Process | NCIT_C29862 | [A sequence of events which produces some outcome.] |
| Triphenylethylene | NCIT_C29863 | [the core chemical structure of a number of related anti-estrogen compounds. The triphenylethylene antiestrogens, which include idoxifene, toremifene, chlorotrianisene, raloxifene and tamoxifen, act at the level of the estrogen receptor, triggering inhibition or stimulation of estrogen-dependent gene transcription and cellular physiology. Triphenylethylenes were initially developed for the treatment of estrogen-dependent breast cancers. Selective estrogen receptor modulators (SERMs) such as raloxifene and tamoxifen represent triphenylethylene derivatives that affect transcriptional regulation through modulation of specific alpha and beta estrogen receptors that are differentially expressed in various normal and neoplastic tissues. (NCI04)] |
| Vinyl Carbamate | NCIT_C29864 | [A synthetic organic compound produced in industry, Vinyl Carbamate is used in biomedical research to induce experimental (especially skin and lung) tumors in animals. Metabolism of Vinyl Carbamate leads to formation of electrophilic reactants that covalently bind to macromolecules (DNA-, RNA-, and protein-adducts) and initiate carcinogenesis. (NCI04)] |
| Zinc Chloride | NCIT_C29865 | [An ionic salt essential for the synthesis of cholesterol, protein, and fats. Zinc plays an important role in the proper functioning of the immune system. Zinc is required for the enzyme activities necessary for cell division, cell growth, and wound healing as well as the release of vitamin A from the liver. It plays a role in the acuity of the senses of smell and taste and is required to maintain prostate reproductive health and insulin function. Zinc is also involved in the metabolism of carbohydrates. Zinc chloride is administered orally or parenterally as a nutritional supplement.] |
| Pirinixic Acid | NCIT_C29866 | [A synthetic thiacetic acid derivative used in biomedical research, carcinogenic Pirinixic acid is a peroxisome proliferator that activates specific peroxisome proliferator-activated receptors (PPAR). PPARs play an important role in diverse cellular functions, including lipid metabolism, cell proliferation, differentiation, adipogenesis, and inflammatory signaling. (NCI04)] |
| Participant | NCIT_C29867 | [Someone who takes part in an activity.] |
| Rhodopsin Kinase | NCIT_C29868 | [Rhodopsin kinase (563 aa, ~64 kDa) is encoded by the human GRK1 gene. This protein plays a role in the regulation of rhodopsin signaling.] |
| Triethylenemelamine | NCIT_C29858 | [A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04)] |
| Ethylenimine Compound | NCIT_C292 | [A compound with a three-atom ring containing nitrogen linked to two carbons. Ethylenimines are highly reactive alkylating reagents.] |
| Grade 2 Mobitz (Type) II Atrioventricular Block, CTCAE | NCIT_C54814 | [Symptomatic; medical intervention indicated] |
| Grade 5 Mucositis Oral, CTCAE | NCIT_C146447 | [Death] |
| Translational Activation | NCIT_C29859 | [Translational Activation consists of cellular and enzymatic reactions that promote the process by which polypeptides are synthesized on ribosomes from information in mRNA transcripts.] |
| Grade 2 AV Block Third Degree, CTCAE | NCIT_C54815 | |
| Grade 2 Bigeminy, CTCAE | NCIT_C54816 | |
| Grade 5 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE | NCIT_C146449 | [Death] |
| Grade 2 Other Cardiac Arrhythmia, CTCAE | NCIT_C54817 | |
| Grade 2 Conduction Abnormality NOS, CTCAE | NCIT_C54818 |