Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Mature Mediastinal Teratoma	NCIT_C7104	[An extragonadal mature teratoma that arises from the mediastinum. It is usually encapsulated and characterized by the presence of unilocular or multilocular cysts. The cysts can contain clear fluid, mucoid material, sebaceous debris, fat, hair, cartilage, and rarely teeth or bone.]
Benign Mediastinal Germ Cell Tumor	NCIT_C6445	[A benign, solid or cystic germ cell tumor that arises from the mediastinum. Solid tumors are classified as benign teratomas. Cystic tumors are classified as dermoid cysts.]
Mediastinal Teratoma	NCIT_C6438	[An extragonadal germ cell tumor that arises from the mediastinum. It is characterized by the presence of somatic tissues derived from two or three of the germ layers (ectoderm, endoderm, and mesoderm).]
Mature Teratoma	NCIT_C9015	[A teratoma which may be cystic; it is composed entirely of well differentiated, adult-type mature tissues, without evidence of fetal-type immature tissues (grade 0 teratoma).]
Grade 4 Spinal Cord Compression, CTCAE	NCIT_C146130	[Life-threatening consequences; urgent intervention indicated]
Spinal Cord Compression, CTCAE	NCIT_C143233	[A disorder characterized by pressure on the spinal cord.]
Exaggerated Placental Site	NCIT_C7105	[A non-neoplastic trophoblastic disorder characterized by the presence of an increased number of implantation-site intermediate trophoblasts infiltrating the endometrium and myometrium extensively. It is associated with pregnancy or abortion.]
Src Kinase-Associated Phosphoprotein 2	NCIT_C29930	[Src kinase-associated phosphoprotein 2 (359 aa, ~41 kDa) is encoded by the human SKAP2 gene. This protein is involved in src and B-cell receptor-dependent signaling pathways.]
Secretin Receptor	NCIT_C29931	[Secretin receptor (440 aa, ~50 kDa) is encoded by the human SCTR gene. This protein plays a role in secretin-dependent G protein-coupled receptor signaling and pancreatid homeostasis.]
Secreted and Transmembrane Protein 1	NCIT_C29932	[Secreted and transmembrane protein 1 (248 aa, ~27 kDa) is encoded by the human SECTM1 gene. This protein may be involved in thymocyte signaling.]
Golgi Apparatus	NCIT_C13238	[A stack of flattened vesicles located between the nucleus and the secretory pole or surface of a cell. Functions in posttranslational processing and sorting of proteins, receiving them from the rough endoplasmic reticulum and directing them to secretory vesicles, lysosomes, or the cell membrane. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or golgi apparatus and fuse with the golgi, lysosomes or cell membrane.]
SECTM1 Gene	NCIT_C24798	[This gene plays a role in hematopoetic and immune system processes.]
Ethnicity	NCIT_C29933	[Ethnicity - an arbitrary classification of the social group a person belongs to, and either identifies with or is identified with by others, as a result of a complex of cultural, biological, geographical and other factors such as linguistic, dietary and religion traditions; ancestry, background, allegiance, or association; and physical characteristics traditionally associated with race. Increasingly the concept is used synonymously with race but this use trend has a pragmatic basis rather than scientific. Also, sImilar to the concept of ethnic origin which is an attempt to classify people, not according to their current ethnicity, but according to where their ancestors came from. Ethnic origin has become a popular classification in statistics, where the concept of race has been largely discarded.]
Magnetic Resonance Spectroscopic Imaging	NCIT_C29934	[Magnetic resonance spectroscopy is a noninvasive imaging technique that acts as a complement to conventional imaging of brain tumors in order to improve the sensitivity and specificity of the diagnostic process. This technique operates by exciting and recording signals from a range of magnetic resonance frequencies, allowing the identification and quantification of several biologically significant molecules containing proton groups that resonate in the appropriate frequency range. The technique facilitates observation of the spatial distribution of metabolic patterns over a region of interest and surrounding tissue at a high spatial resolution.]
EF-Hand Domain	NCIT_C13956	[Forming a single Ca2+-binding site in many calcium-binding proteins, the basic EF-Hand Domain consists of a conserved 12-residue loop region between two perpendicular 10-12 residue alpha helices (helix-loop-helix). Ca2+ interacts with loop residues in a pentagonal bipyramidal configuration; each loop residue is important for Ca2+ coordination. Loop residues 1, 3, 5, 7, 9, and 12 (invariant Glu or Asp) are directly necessary for Ca2+ binding. Amino-acid variations at positions 1, 3, 5, 7, and 9 alter ion affinity. Single or multiple domains cause structural/functional variations. EF-hand Proteins are grouped into either regulatory/signaling or structural/buffering/transport categories. Ca2+ binding to regulatory proteins induces conformational/functional change; Ca2+ binding to structural proteins seems to provide a Ca2+ buffer. (NCI)]
S100 Family Gene	NCIT_C20849	[S100 Family Gene members, many clustered on chromosome 1q21, encode S100 Calcium Binding Proteins localized in the cytoplasm and/or nucleus of many cells that often regulate cellular processes such as cell cycle progression and differentiation.]
Grade 4 Suicide Attempt, CTCAE	NCIT_C146139	[Suicide attempt with intent to die which requires hospitalization]
Suicide Attempt, CTCAE	NCIT_C143865	[A disorder characterized by self-inflicted harm in an attempt to end one's own life.]
Protein S100-A11	NCIT_C29925	[Protein S100-A11 (105 aa, ~12 kDa) is encoded by the human S100A11 gene. This protein is involved in calcium binding and keratinocyte differentiation.]
Protein S100-A12	NCIT_C29926	[Protein S100-A12 (92 aa, ~11 kDa) is encoded by the human S100A12 gene. This protein plays a role in calcium, zinc, and copper binding and in the regulation of inflammatory processes.]